Sr. Scientist Immunology

Yoh is a seeking a Sr. Scientist Immunology to support a San Francisco Bay Area based startup company in the biotechnology industry. You will have the opportunity to support antibody therapeutics! Responsibilities include executing histopathology techniques for evaluating tumor and immune cell therapeutic targets and supervising RAs.

Title: Sr. Scientist Immunology
Location: San Jose, Ca
Industry: Biotechnology
Pay: Competitive, depends on experience

Summary:

• Design, develop, and execute translational immunohistochemistry (IHC) and multiplexed immunofluorescence assays, and tissue-based special transcriptomics biomarker assays to support patient stratification, pharmacodynamics, deciphering the mechanism of action, evaluate efficacy & toxicity, and prediction of clinical response from early discovery to first in human proof of concept
• Developing expertise around target proteins and their expression profiles in oncology indications of interest
• Develop and execute tissue-based experiments, including validation of antibodies, in preclinical models
• Identify and evaluate new technologies to support our client's evolving biomarker strategies including digital image analysis and deep learning
• Responsible for overseeing data analyses and delivery of decisional data of CRO-based projects
• Effectively collaborate in highly matrixed organization to drive advancement of early stage projects into translational and clinical development
• Managerial experience with direct reports

 Requirements:

• PhD in the Life Sciences, with experience in cell and molecular biology lab techniques, preference for histology experience 
• Extensive experience in histology, normal and diseased tissue sample preparation, sectioning (cryostat and microtome), immunohistochemistry, in situ hybridization, and microscopy
• Extensive experience with chromogenic and fluorescent staining (mono and multiplex) on pre-clinical, non-clinical and clinical samples.
• Expertise with manual/automated microscopy (Bright Field and Fluorescent) and image analysis software and platforms
• Strong track record of developing and implementing strategic initiatives to improve scientific and/or operational activities
• Experience working with service providers and CROs
• Excellent organization skills and familiarity with a fast-paced work environment
• Collaborative spirit and ability to thrive in a matrixed environment

Preferred Qualifications:

• Tissue culture, flow cytometry, immune cell culture experience
• Knowledge of tumor pathology, cancer biology and immuno-oncology

Note: Any pay ranges displayed are estimations.  Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description.  All qualified applicants are welcome to apply.

Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Visit [ Link removed ] - Click here to apply to Sr. Scientist Immunologyto contact us if you are an individual with a disability and require accommodation in the application process.

Salary : $140,000 - $160,000