Department:. Translational Medicine. Reports to:. Director, Translational Sciences. Location:. Cambridge, MA. Casma Overview. Casma Therapeutics is harnessing the natural cellular process of autophagy to open vast new target areas for drug discovery and development that will profoundly impact the lives of patients. Autophagy is a conserved cellular process that contributes to overall organismal health. Inefficient autophagy flux or defects in lysosomal homeostasis are observed in numerous pathologies, e.g., neurodegeneration, metabolic disorders, inflammation, and muscle degeneration. Casma us... view job details
Department: Biology. Reports to: Senior Scientist II, Biology. Location: Cambridge, MA. Casma Overview. Autophagy is a conserved cellular process that contributes to overall organismal health; inefficient autophagic flux is observed in numerous diseases. Casma Therapeutics is harnessing autophagy by developing a novel degradation technology to open new target areas for drug discovery and development that will profoundly impact the lives of patients. By selectively boosting autophagy, Casma expects to be able to arrest or reverse the ... view job details