Technology Manager jobs in the United States

Associate Principal Engineer, Antibody Drug Conjugates - Process
  • 50085962 - Engineering Technology Manager
  • Gaithersburg, MD FULL_TIME
  • Are you ready to make a significant impact on patients' lives? As the Associate Director of Antibody Drug Conjugate (ADC) Manufacturing Process, you will be responsible for developing, characterizing, and validating conjugation and associated purification platform unit operations within our biologics Global Technical Operations (GTO). You will work closely with BioPharmaceutical Development and other members of the New Modalities Team to build the requisite technical knowledge to plan and execute activities internally and/or at third parties.

    Your role will involve leading activities related to ADC conjugation and associated purification unit operations platforms within Biologics GTO to achieve optimized manufacturing processes regarding productivity, product quality and SHE (Safety, Health & Environmental). This will involve building the requisite technical knowledge to plan and execute the development, characterization, and validation of relevant unit operations internally and/or at third parties with other departments.

    Essential Skills/Experience:

    • Bachelor’s degree in engineering, biochemistry or related field: 12 years of experience with Bachelors degree; 9 years with Masters; and 6 years with Ph.D.

    • Minimum of ten years of significant engineering or operational experience.

    • Excellent problem-solving abilities.

    • Strong interpersonal, organizational, collaboration and communication skills.

    • Demonstrated ability to develop, characterize (involving DOEs) and validate (performance qualification) drug substance purification manufacturing processes.

    • Deep knowledge of ADC conjugation:

    • Chemistries (mabs, linkers and cytotoxic payloads), process parameters affecting yield and product quality like purity (i.e. generation of product-related substance impurities) and potency.

    • Associated purification unit operations such ultrafiltration/diafiltration (UF/DF) and various modes of chromatography (ion exchange, hydrophobic interaction, multi-mode).

    • Knowledge of current Good Manufacturing Practices (cGMPs) and relevant SHE (Safety, Health & Environmental) laws, regulations, and guidance, especially those related to the conjugation operations.

    • Experience leading a project with cross-functional internal and external teams.

    Desirable Skills/Experience:

    • -Master’s or Ph.D. degree is preferred.

    When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

    Why AstraZeneca?
    In Operations we have a big ambition. To deliver more medicines to patients, quicker and more affordably. Backed by the investment, leadership and a clear plan to get there, we bring personal dedication and out of the box thinking. We are driven by our commitment to deliver accelerated growth for AstraZeneca and to make people's lives better. It pushes us to keep building on our foundations and progressing as we turn our ever-growing and increasingly complex pipeline from molecule to medicine. Be part of evolving how we work with Lean, cutting-edge science, digitalisation and sustainable practices.

    Are you ready to embrace a long-term, varied career in a fast-paced, growing environment? With a huge variety of global opportunities and learning from other teams this is the place to embrace lifelong learning and build capabilities, setting your own direction and pace. Apply today!

    AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

    AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

  • 6 Days Ago

Information Technology Manager
  • Planet Technology
  • Dayton, OH FULL_TIME
  • Perm RoleOn site - Dayton OH area IT Manager You will provide senior level IT support operations for a manufacturing plant in Troy, OH. The role will span from desktop, server, networking, etc. with a...
  • Just Posted

Information Technology Manager
  • Planet Technology
  • Magnolia, AR FULL_TIME
  • ***Onsite Role - Relocation Assistance Available******NO 3RD PARTIES OR C2C***ERP/IT ManagerOur client is a leading provider of high-quality furnishings, committed to providing exceptional products an...
  • 8 Days Ago

Information Technology Project Manager
  • Planet Technology
  • Waltham, MA CONTRACTOR
  • IT Project ManagerThis person will lead projects to launch and to continue support of Information Technology solutions that span hardware, software and services, in a continuous effort to provide worl...
  • 11 Days Ago

Program Manager - Security Technology Integration
  • ISPA Technology
  • Panama, FL FULL_TIME
  • Job Title: Program Manager - Security Technology IntegrationLocation: Panama City Beach, FLJob Overview: Embark on a thrilling journey as a Program Manager for Security Technology Integration, where y...
  • 1 Day Ago

Customer Success Manager - Insurance Technology
  • Shift Technology
  • Boston, MA FULL_TIME
  • The future of insurance starts with AI. To date, Shift Technology's AI-powered products have benefitted more than 300 million policyholders globally by reducing underwriting risk, identifying more fra...
  • 5 Days Ago

Digital Design and Technology Manager
  • Hickok Cole
  • Washington, DC
  • Job Summary: The Digital Design and Technology Manager is responsible for working with firm principles, key project desi...
  • 6/22/2024 12:00:00 AM

Manager of Technology
  • Howard University
  • Washington, DC
  • The Talent Acquisition department hires qualified candidates to fill positions which contribute to the overall strategic...
  • 6/22/2024 12:00:00 AM

ECS Senior Manager, Construction Technology & Integration
  • Mc Lean, VA
  • Job Title: ECS Senior Manager, Construction Technology & Integration Reports to: Senior Director, Virtual Design and Con...
  • 6/22/2024 12:00:00 AM

ECS Senior Manager, Construction Technology & Integration
  • EMCOR Group, Inc.
  • Mc Lean, VA
  • Job Title: ECS Senior Manager, Construction Technology & Integration Reports to: Senior Director, Virtual Design and Con...
  • 6/22/2024 12:00:00 AM

Manager, HR Technology (Compensation)
  • Marriott International
  • Bethesda, MD
  • Job Description JOB SUMMARY *This is a hybrid role based out of our Bethesda, MD Headquarters. *This is an individual co...
  • 6/22/2024 12:00:00 AM

Forensic Technology Manager
  • Clifford Chance
  • Washington, DC
  • Company Description Who we are We are one of the largest international law firms in the world. With over 30 offices acro...
  • 6/20/2024 12:00:00 AM

Information Technology Manager
  • Judge Consulting Group
  • Vienna, VA
  • IT Manager, Systems & Cloud Engineering: The Manager of Systems & Cloud Engineering is the primary subject matter expert...
  • 6/18/2024 12:00:00 AM

Metrics Analyst
  • Imagine One Technology & Management
  • Washington, DC
  • 6/18/2024 12:00:00 AM

Income Estimation for Technology Manager jobs
$104,650 to $128,973