Clinical Information Systems Director Salary in Missouri

How much does a Clinical Information Systems Director make in Missouri?

As of August 01, 2026, the average salary for a Clinical Information Systems Director in Missouri is $164,000 per year, which breaks down to an hourly rate of $79.

However, a Clinical Information Systems Director's salary can vary significantly. Here’s a look at the typical salary range:

• Top Earners (90th percentile): $185,970
• Majority Range (25th-75th percentile): $147,200 to $175,500
• Entry-Level (10th percentile): $131,904