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Clinical Study Project Manager III Salary in the United States

How much does a Clinical Study Project Manager III make in the United States?

As of July 01, 2026, the average salary for a Clinical Study Project Manager III in the United States is $100,900 per year, which breaks down to an hourly rate of $49.

However, a Clinical Study Project Manager III's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $123,252
  • Majority Range (25th-75th percentile): $89,400 to $112,600
  • Entry-Level (10th percentile): $78,930
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View as table View as graph 25% $89,400 10% $78,930 90% $123,252 75% $112,600 $100,900 50%(Median) Didn’t find job title? Click

Clinical Study Project Manager III Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $112,600 $9,383 $2,165 $54
Average $100,900 $8,408 $1,940 $49
25th Percentile $89,400 $7,450 $1,719 $43
Check out Clinical Study Project Manager III Job Openings in the United States
Operations Project Manager III

Jabil Circuit, Inc. - Aberdeen, OH

Project Manager III

VeregyLLC - Columbus, OH

Project Manager III

PNC Bank Corp. - Columbus, OH

Clinical Trial Project Manager

Medpace - Cincinnati, OH

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Key Factors That Influence Clinical Study Project Manager III Salaries

A Clinical Study Project Manager III's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.

How Experience Level Affects Clinical Study Project Manager Salaries?

Experience is a primary driver of a Clinical Study Project Manager III's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Study Project Manager I (0-2 years): $62,898
  • Clinical Study Project Manager II (2-4 years): $86,101
  • Clinical Study Project Manager III (4-7 years): $100,836
  • Clinical Study Project Manager IV (7+ years): $114,706
  • Clinical Study Project Manager V (7-10 years): $141,634
Job Role Years of Experience Average Salary
Clinical Study Project Manager I0-2 years$62,898
Clinical Study Project Manager II2-4 years$86,101
Clinical Study Project Manager III4-7 years$100,836
Clinical Study Project Manager IV7+ years$114,706
Clinical Study Project Manager V7-10 years$141,634
$62,898 Clinical ...
$86,101 Clinical ...
$100,836 Clinical ...
$114,706 Clinical ...
$141,634 Clinical ...
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What Am I Worth?

How Do Clinical Study Project Manager III Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Study Project Manager IIIs. For example, consider the average annual salaries in these key locations:

  • District of Columbia: $111,700.
  • California: $111,300.
  • Massachusetts: $109,800.

Top Paying Cities for Clinical Study Project Manager IIIs

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $127,200
  • San Francisco: $125,800
  • Oakland: $123,200

Clinical Study Project Manager III Salary by Company Size: Startups vs. Enterprise

Clinical Study Project Manager III salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $114,429. While startup companies pay approximate $97,076.

Clinical Study Project Manager III Salary by Company Size

Company Size Employees Average Salary
Startup1~50$97,076
Growth Stage51~500$102,589
Established501~5000$110,581
Enterprise5000+$114,429

Clinical Study Project Manager III Salary by Industry: Top Paying Sectors

For Clinical Study Project Manager III roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Biotechnology and Healthcare sectors offer the strongest compensation, at 20% above the average. In contrast, Clinical Study Project Manager positions in Chemicals or Edu., Gov't. & Nonprofit typically offer lower base pay, as these industries often view Clinical Study Project Manager III as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Study Project Manager III

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Biotechnology$121,080$58.020%
Healthcare$110,990$53.010%

Clinical Study Project Manager III Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Study Project Manager III's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on July 01, 2026

Clinical Study Project Manager III Salary Growth & Career Path

For a Clinical Study Project Manager III, the most direct path to higher earnings is advancing to the Clinical Study Project Manager IV role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $114,800 - a projected growth of 14% over your current level.

Most common benefits for Clinical Study Project Manager III

Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
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Common company salaries for Clinical Study Project Manager III

Here are companies hiring for Clinical Study Project Manager III and their salaries, click below for more details.

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FAQ about Clinical Study Project Manager III

1. What industry pays the highest salary for Clinical Study Project Manager III?

The Biotechnology industry offers the highest average compensation for Clinical Study Project Manager III roles, with salaries approximately 20% above the market median.

2. What degree do you need to be a clinical manager?

To become a clinical manager, a bachelor's or master's degree in business administration, health administration, management, or public health administration is typically required. Degrees in nursing or nursing management are also relevant. Most master's programs include fieldwork in a clinical setting. Salaries for Clinical Study Project Managers range from $114,000 to $140,200, with a median of $126,000.

3. How much do study managers make in the US?

In the US, Clinical Study Project Managers earn between $114,000 and $140,200 annually. The average salary is around $126,000, reflecting a more competitive range compared to other roles in the field. This positions them well above the typical earnings reported for Global Study Managers.

4. How much does a clinical study team lead make at Pfizer?

The annual base salary for a Clinical Study Project Manager typically ranges from $114,000 to $140,200, with a midpoint of $126,000. This reflects the competitive compensation for professionals in this role, ensuring alignment with industry standards.

5. How much do clinical project managers make in the US?

Clinical Study Project Managers in the US earn between $114,000 and $140,200 annually, with a median salary of approximately $126,000. These figures reflect the salary range based on industry data, providing a clear picture of compensation for this role.

6. What does a clinical project manager do?

A clinical project manager oversees the entire clinical trial process, from selecting participants to reporting results. Their responsibilities include establishing a plan or protocol, determining necessary tests, and ensuring compliance with scientific standards and government regulations. The salary for this role ranges from $114,000 to $140,200, with a midpoint of $126,000.

7. What is the highest salary for a clinical trial manager?

The highest salary for a Clinical Study Project Manager is $140,200 per year. The minimum salary starts at $114,000, while the mid-range salary is $126,000. These figures reflect the compensation landscape for this role in the industry.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

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