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Clinical Informatics Manager Salary in the United States

How much does a Clinical Informatics Manager make in the United States?

As of August 01, 2026, the average salary for a Clinical Informatics Manager in the United States is $139,105 per year, which breaks down to an hourly rate of $67.

However, a Clinical Informatics Manager's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $168,341
  • Majority Range (25th-75th percentile): $128,134 to $154,408
  • Entry-Level (10th percentile): $118,145

Key Factors That Influence Clinical Informatics Manager Salaries

A Clinical Informatics Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Clinical Informatics Manager Salaries?

Experience is a primary driver of a Clinical Informatics Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Informatics Analyst II (2-4 years): $92,154
  • Clinical Informatics Analyst III (4-7 years): $111,340
  • Clinical Informatics Manager (7+ years): $139,105
  • Clinical Informatics Senior Manager (7+ years): $155,895
  • Clinical Informatics Director (7+ years): $172,587
Job Role Years of Experience Average Salary
Clinical Informatics Analyst II2-4 years$92,154
Clinical Informatics Analyst III4-7 years$111,340
Clinical Informatics Manager7+ years$139,105
Clinical Informatics Senior Manager7+ years$155,895
Clinical Informatics Director7+ years$172,587

Top Paying Cities for Clinical Informatics Manager

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $175,453
  • San Francisco: $173,532
  • Oakland: $169,875

Clinical Informatics Manager Salary by Company Size: Startups vs. Enterprise

Clinical Informatics Manager salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $156,526. While startup companies pay approximate $132,947.

Clinical Informatics Manager Salary by Company Size

Company Size Employees Average Salary
Startup 1~50 $132,947
Growth Stage 51~500 $140,457
Established 501~5000 $151,289
Enterprise 5000+ $156,526

Clinical Informatics Manager Salary by Industry: Top Paying Sectors

For Clinical Informatics Manager roles, the industry you choose can affect earning potential by as much as 100% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Edu., Gov't. & Nonprofit sectors offer the strongest compensation, at 50% above the average. In contrast, Clinical Informatics Manager positions in Pharmaceuticals or Biotechnology typically offer lower base pay, as these industries often view Clinical Informatics Manager as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Informatics Manager

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$208,658$100.050%
Edu., Gov't. & Nonprofit$153,016$74.010%

Clinical Informatics Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Informatics Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on August 01, 2026
$128,134
Average $139,105/year
$154,408
$10,678
Average $11,592/month
$12,867
$2,464
Average $2,675/week
$2,969
$62
Average $67/hour
$74
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $154,408 $12,867 $2,969 $74
Average $139,105 $11,592 $2,675 $67
25th Percentile $128,134 $10,678 $2,464 $62

Clinical Informatics Manager Salary Growth & Career Path

For a Clinical Informatics Manager, the most direct path to higher earnings is advancing to the Clinical Informatics Senior Manager role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $155,895 - a projected growth of 12% over your current level.

Most common benefits for Clinical Informatics Manager

  • Social Security
  • 401 (k)
  • Disability
  • Healthcare
  • Pension
  • Time Off (days)

Common company salaries for Clinical Informatics Manager

Here are companies hiring for Clinical Informatics Manager and their salaries, click below for more details.

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FAQ about Clinical Informatics Manager

1. Where can a Clinical Informatics Manager earn the most?

A Clinical Informatics Manager's earning potential can vary widely depending on several factors, including location, industry, experience, education, and the specific employer. According to the latest salary data by Salary.com, a Clinical Informatics Manager earns the most in San Jose, CA, where the annual salary of a Clinical Informatics Manager is $175,453.

2. What is the highest pay for Clinical Informatics Manager?

The highest pay for Clinical Informatics Manager is $168,341.

3. What is the lowest pay for Clinical Informatics Manager?

The lowest pay for Clinical Informatics Manager is $118,145.

4. What are the responsibilities of Clinical Informatics Manager?

Manages the implementation, maintenance, and analysis of data from clinical informatics systems. Oversees the implementation of electronic health record (EHR) systems, bed management systems, computerized physician order entry systems, or any other relevant health information systems. Analyzes and reviews data produced by these systems to identify trends and areas for improvement and to ensure systems are functioning properly. Evaluates and establishes initiatives to improve systems or integrate new systems. May provide staff training on new or updated systems. Requires a bachelor's degree. Typically reports to a director. Manages subordinate staff in the day-to-day performance of their jobs. True first level manager. Ensures that project/department milestones/goals are met and adhering to approved budgets. Has full authority for personnel actions. Typically requires 5 years experience in the related area as an individual contributor. 1-3 years supervisory experience may be required. Extensive knowledge of the function and department processes.

5. What industry pays the highest salary for Clinical Informatics Manager?

The Healthcare industry offers the highest average compensation for Clinical Informatics Manager roles, with salaries approximately 50% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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