Informatics Nurse Specialist Salary in the United States

How much does an Informatics Nurse Specialist make in the United States?

As of October 01, 2026, the average salary for an Informatics Nurse Specialist in the United States is $110,124 per year, which breaks down to an hourly rate of $53.

However, an Informatics Nurse Specialist's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $127,864
  • Majority Range (25th-75th percentile): $99,296 to $119,410
  • Entry-Level (10th percentile): $89,437

Key Factors That Influence Informatics Nurse Specialist Salaries

An Informatics Nurse Specialist's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

How Experience Level Affects Informatics Nurse Specialist Salaries?

Experience is a primary driver of an Informatics Nurse Specialist's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $74,050
  • Early Career (1-2 years): $93,009
  • Mid-Level (2-4 years): $112,380
  • Senior-Level (5-8 years): $140,416
  • Expert (over 8 years): $157,337
Levels Salary
Clinical ... Level Informatics Nurse Specialist$74,050
Clinical ... Level Informatics Nurse Specialist$93,009
Informati... Level Informatics Nurse Specialist$112,380
Clinical ... Level Informatics Nurse Specialist$140,416
Clinical ... Level Informatics Nurse Specialist$157,337

Top Paying Cities for Informatics Nurse Specialists

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $138,899
  • San Francisco: $137,379
  • Oakland: $134,483

What Skills Can Increase an Informatics Nurse Specialist's Salary?

Demanded Skills for the Role:

  • Analysis (Mentioned in 5.4% Job Postings): Analysis is the process of considering something carefully or using statistical methods in order to understand it or explain it.
  • Integrated Care (Mentioned in 2.58% Job Postings): It is care that is planned with people who work together to understand the service user and their carer(s), puts them in control and coordinates and delivers services to achieve the best outcomes.
  • Patient Safety (Mentioned in 1.51% Job Postings): Patient safety is a discipline and responsibility that emphasizes safety in health care through the prevention, reduction, reporting, and analysis of medical error that often leads to adverse effects. The frequency and magnitude of avoidable adverse events experienced by patients was not well known until the 1990s, when multiple countries reported staggering numbers of patients harmed and killed by medical errors. Recognizing that healthcare errors impact 1 in every 10 patients around the world, the World Health Organization calls patient safety an endemic concern. Indeed, patient safety has emerged as a distinct healthcare discipline supported by an immature yet developing scientific framework. There is a significant transdisciplinary body of theoretical and research literature that informs the science of patient safety. At the same time, efforts are being made to anchor patient safety more firmly in medical education. The resulting patient safety knowledge continually informs improvement efforts such as: applying lessons learned from business and industry, adopting innovative technologies, educating providers and consumers, enhancing error reporting systems, and developing new economic incentives.
Skills Demand Percentage
Analysis 5.4%
Integrated Care 2.58%
Patient Safety 1.51%

What skills can make your compensation higher?

Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on an Informatics Nurse Specialist's salary.

  • Decision Making: Can increase your salary by up to 5%.
  • Flexibility: Can increase your salary by up to 5%.
  • Innovation: Can increase your salary by up to 4%.
Skill Salary Salary % Increase
Decision Making $115,630
5%
Flexibility $115,630
5%
Innovation $114,529
4%

Informatics Nurse Specialist Salary by Industry: Top Paying Sectors

For Informatics Nurse Specialist roles, the industry you choose can affect earning potential by as much as 35% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Pharmaceuticals sectors offer the strongest compensation, at 15% above the average. In contrast, Informatics Nurse Specialist positions in Biotechnology or Edu., Gov't. & Nonprofit typically offer lower base pay, as these industries often view Informatics Nurse Specialist as a support function rather than a direct revenue driver.

The top paying industries for an Informatics Nurse Specialist

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$126,643$61.015%
Pharmaceuticals$121,136$58.010%

How Education impacts an Informatics Nurse Specialist's Salary?

Your level of education can impact your salary potential. While many Informatics Nurse Specialists enter the field with a Bachelor's Degree degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for an Informatics Nurse Specialist with a Bachelor's Degree is between $97,150 and $104,214).

Informatics Nurse Specialist Salaries by Degree Level

Typical Education for Informatics Nurse Specialist
Degree Level % of user with this level of education
No Diploma 7.2%
High School 7.2%
Associates 13.2%
Bachelors 39.5%
Masters 38.3%
Doctorate 1.8%

Informatics Nurse Specialist Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how an Informatics Nurse Specialist's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on October 01, 2026
$99,296
Average $110,124/year
$119,410
$8,275
Average $9,177/month
$9,951
$1,910
Average $2,118/week
$2,296
$48
Average $53/hour
$57
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $119,410 $9,951 $2,296 $57
Average $110,124 $9,177 $2,118 $53
25th Percentile $99,296 $8,275 $1,910 $48

Most common benefits for Informatics Nurse Specialist

  • Social Security
  • 401 (k)
  • Disability
  • Healthcare
  • Pension
  • Time Off (days)

Common company salaries for Informatics Nurse Specialist

Here are companies hiring for Informatics Nurse Specialist and their salaries, click below for more details.

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FAQ about Informatics Nurse Specialist

1. What industry pays the highest salary for Informatics Nurse Specialist?

The Healthcare industry offers the highest average compensation for Informatics Nurse Specialist roles, with salaries approximately 15% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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