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As of August 01, 2026, the average salary for a Medical Practice Assistant in South Carolina is $41,298 per year, which breaks down to an hourly rate of $20.
However, a Medical Practice Assistant's salary can vary significantly. Here’s a look at the typical salary range:
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Medical Practice Assistant Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $45,113 | $3,759 | $868 | $22 |
| Average | $41,298 | $3,441 | $794 | $20 |
| 25th Percentile | $36,716 | $3,060 | $706 | $18 |
Barefoot Oral and Maxillofacial Sur - Mount Pleasant, SC
Legal Solutions Group - Mount Pleasant, SC
Medical University of South Carolina - Florence, SC
Medical University of South Carolina - Marion, SC
A Medical Practice Assistant's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Medical Practice Assistant's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Medical Practice Assistant | $41,934 |
| Intermediate Level Medical Practice Assistant | $42,369 |
| Senior Level Medical Practice Assistant | $43,245 |
| Specialist Level Medical Practice Assistant | $43,420 |
| Expert Level Medical Practice Assistant | $43,537 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Medical Practice Assistants. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Medical Practice Assistant roles, the industry you choose can impact your earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Healthcare, offers compensation 20% above the average. Conversely, Medical Practice Assistant positions in Edu., Gov't. & Nonprofit typically offer lower base pay, as this sector often view Medical Practice Assistant as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Healthcare | $49,557 | $24.0 | 20% |
Understanding how a Medical Practice Assistant's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $45,113 | $3,759 | $868 | $22 |
| Average | $41,298 | $3,441 | $794 | $20 |
| 25th Percentile | $36,716 | $3,060 | $706 | $18 |
Ready to take the next step in your career? Browse thousands of current Medical Practice Assistant job openings on our job board. Use the search bar below to find your perfect match.
Northeast Healthcare Recruitment
Laurens, SC
Northeast Healthcare Recruitment | Laurens, SC
We are seeking a dedicatedand experienced Nurse Practitioner or Physician Assistant to join our FamilyMedicine team as a floating provider. This role will ... more
6 Days Ago
Healthcare Recruitment Counselors
Conway, SC
Healthcare Recruitment Counselors | Conway, SC
Nurse Practitioner OR Physician Assistant Conway SC (15 miles NW of Myrtle Beach)Urgently Hiring4-day work week$125k/yr plus performance bonuses and profit... more
6 Days Ago
Source Medical, LLC
Vance, SC
Source Medical, LLC | Vance, SC
Family Nurse Practitioner opening in South CarolinaLocated in Vance, SC - Columbia 50mFull-time. PermanentFQHC Responsibilities:Provide direct patient care... more
6 Days Ago
Provider Healthcare
Greenville, SC
Provider Healthcare | Greenville, SC
Looking for flexibility now with the option to transition into a long-term role. Join us as a Physician Assistant in South Carolina with Locums-to-Permanen... more
6 Days Ago
Novant Health
Hardeeville, SC
Novant Health | Hardeeville, SC
What We OfferJob Title:Night Nurse Practitioner - Coastal Carolina HospitalLocation: Coastal Carolina Hospital, Hardeeville, SC 1000 Medical Center Dr, Har... more
6 Days Ago
DirectShifts
Sumter, SC
DirectShifts | Sumter, SC
Position Summary. The provider will review Veterans' medical records, conduct comprehensive General Medicine examinations, document objective findings, and... more
10 Days Ago
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