Medical Practice Assistant Salary in South Dakota

How much does a Medical Practice Assistant make in South Dakota?

As of August 01, 2026, the average salary for a Medical Practice Assistant in South Dakota is $40,055 per year, which breaks down to an hourly rate of $19.

However, a Medical Practice Assistant's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $47,125
  • Majority Range (25th-75th percentile): $35,611 to $43,756
  • Entry-Level (10th percentile): $31,565
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View as table View as graph 25% $35,611 10% $31,565 90% $47,125 75% $43,756 $40,055 50%(Median) Didn’t find job title? Click

Medical Practice Assistant Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $43,756 $3,646 $841 $21
Average $40,055 $3,338 $770 $19
25th Percentile $35,611 $2,968 $685 $17
Check out Medical Practice Assistant Job Openings in South Dakota
Family Practice Primary Care Physician Assistant

iRecruitMD - Custer, SD

Family Practice Nurse Practitioner or Physician Assistant

Faulkton Area Medical Center - Faulkton, SD

Family Practice Primary Care Physician Assistant

Summit Recruiting Group LLC - Rapid City, SD

Family Practice Primary Care Physician Assistant

DirectShifts - Pierre, SD

Search More Medical Practice Assistant Jobs in South Dakota

Key Factors That Influence Medical Practice Assistant Salaries

A Medical Practice Assistant's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Medical Practice Assistant Salaries?

Experience is a primary driver of a Medical Practice Assistant's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $40,672
  • Early Career (1-2 years): $41,094
  • Mid-Level (2-4 years): $41,943
  • Senior-Level (5-8 years): $42,113
  • Expert (over 8 years): $42,226
Levels Salary
Entry Level Medical Practice Assistant$40,672
Intermediate Level Medical Practice Assistant$41,094
Senior Level Medical Practice Assistant$41,943
Specialist Level Medical Practice Assistant$42,113
Expert Level Medical Practice Assistant$42,226
$40,672 0 yr
$41,094 < 2 yrs
$41,943 2-4 yrs
$42,113 5-8 yrs
$42,226 > 8 yrs
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What Am I Worth?

Top Paying Cities for Medical Practice Assistants

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • Alcester: $40,472
  • Aurora: $40,687
  • Baltic: $40,249

Medical Practice Assistant Salary by Industry: Top Paying Sectors

For Medical Practice Assistant roles, the industry you choose can impact your earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Healthcare, offers compensation 20% above the average. Conversely, Medical Practice Assistant positions in Edu., Gov't. & Nonprofit typically offer lower base pay, as this sector often view Medical Practice Assistant as a support function rather than a direct revenue driver.

The top paying industry for a Medical Practice Assistant

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$48,066$23.020%

Medical Practice Assistant Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Medical Practice Assistant's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on August 01, 2026

Find Your Next Medical Practice Assistant Job

Ready to take the next step in your career? Browse thousands of current Medical Practice Assistant job openings on our job board. Use the search bar below to find your perfect match.

United States
  • iRecruitMD

    Rapid City, SD

    iRecruitMD | Rapid City, SD

    Neonatal Nurse Practitioner / Physician Assistant (NP/PA) Position Summary. The Neonatal Nurse Practitioner or Physician Assistant provides comprehensive m... more

    11 Days Ago

  • Archway Physician Recruitment

    Custer, SD

    Archway Physician Recruitment | Custer, SD

    Full-Time APP - Family Medicine Custer, SD1+ years of Clinical and Healthcare ExperienceJob Summary:•Under physician supervision, the Physician Assistant (... more

    17 Days Ago

  • Vision Quest Solutions Inc

    Wagner, SD

    Vision Quest Solutions Inc | Wagner, SD

    Job Description. Job Description. Description. Vision Quest Solutions is seeking experienced Nurse Practitioners (NPs) and Physician Assistants (PAs) to pr... more

    5 Days Ago

  • Shah Medical Clinic

    Sioux Falls, SD

    Shah Medical Clinic | Sioux Falls, SD

    Job Description. Job Description. Join Our Compassionate Team at Shah Medical Clinic. Are you a caring and dedicated individual looking to make a positive ... more

    2 Days Ago

  • The Wellness Collective

    Sioux Falls, SD

    The Wellness Collective | Sioux Falls, SD

    Job Description. Job Description. Part-Time Medical Assistant (MA). Sioux Falls, SD | Approximately 24 hours per week. Are you a compassionate, organized n... more

    4 Days Ago

  • Rushmore Dermatology, LLP

    Rapid City, SD

    Rushmore Dermatology, LLP | Rapid City, SD

    Job Description. Job Description. "Medical Assistant -Dermatology". Monday–Friday, no weekends. Join a Growing, Physician-Owned Dermatology Practice more

    5 Days Ago

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Cost of Living In South Dakota

Cost of Living in South Dakota is
-9.1% Lower
than the National Average

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