What are the main factors that influence a Clinical Data Manager II's salary?

The primary factors are: 1) Experience Level, 2) Geographic Location, 3) Education/Skills, 4) Company Size & Industry

How does experience change A Clinical Data Manager 's salary?

A Clinical Data Manager II's salary grows with experience: starting around $139,523 for beginners, reaching about $143,849 at mid-level, and approach $150,877 for experts.

What are the highest paying states for a Clinical Data Manager II?

Clinical Data Manager II salary varies significantly by state. The top 3 highest paying states for Clinical Data Manager II roles are District of Columbia $160,825, California $160,215, Massachusetts $158,080. These tech hubs typically pay 10-15% above the national average.

How much do different types of Clinical Data Manager roles make?

Salaries for Clinical Data Manager level roles vary by specialization: Clinical Data Manager: $144,586; Clinical Statistician II: $108,990; Clinical Data SAS Programmer II: $97,990; Clinical Data Insights Developer II: $97,960; Clinical Programmer II: $97,960.

How do different companies affect a Clinical Data Manager II's salary?

Company size, industry, and compensation structure create significant salary variations for Clinical Data Manager II roles. Large, established industry leaders like C R Bard Inc ($128,509) and Henry Schein Canada ($124,697) offer base salaries 35-40% above the national average. In contrast, smaller firms or startups may offer closer to $82,041.

Clinical Data Manager II Salary in the United States

How much does a Clinical Data Manager II make in the United States?

As of June 01, 2026, the average salary for a Clinical Data Manager II in the United States is $145,254 per year, which breaks down to an hourly rate of $70.

However, a Clinical Data Manager II's salary can vary significantly. Here’s a look at the typical salary range:

Top Earners (90th percentile): $181,778
Majority Range (25th-75th percentile): $133,294 to $164,372
Entry-Level (10th percentile): $122,405

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Clinical Data Manager II Salaries by Percentile

	Annual Salary	Monthly Pay	Weekly Pay	Hourly Wage
75th Percentile	$164,372	$13,698	$3,161	$79
Average	$145,254	$12,105	$2,793	$70
25th Percentile	$133,294	$11,108	$2,563	$64

You may get higher pay by adjusting the following factors:

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Key Factors That Influence Clinical Data Manager II Salaries

A Clinical Data Manager II's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

How Experience Level Affects Clinical Data Manager II Salaries?

Experience is a primary driver of a Clinical Data Manager II's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

Entry-Level (less than 1 year): $139,523
Early Career (1-2 years): $140,042
Mid-Level (2-4 years): $143,849
Senior-Level (5-8 years): $150,034
Expert (over 8 years): $150,877

Levels	Salary
Entry Level Clinical Data Manager II	$139,523
Intermediate Level Clinical Data Manager II	$140,042
Senior Level Clinical Data Manager II	$143,849
Specialist Level Clinical Data Manager II	$150,034
Expert Level Clinical Data Manager II	$150,877

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What Am I Worth?

How Do Clinical Data Manager II Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Data Manager IIs. For example, consider the average annual salaries in these key locations:

District of Columbia: $160,825.
California: $160,215.
Massachusetts: $158,080.

District of Columbia $160,825

California $160,215

Massachusetts $158,080

Washington $157,499

New Jersey $157,441

Alaska $157,237

Connecticut $155,233

New York $154,420

Hawaii $151,819

Rhode Island $150,599

Maryland $149,771

Minnesota $148,638

Colorado $148,203

Illinois $148,057

Oregon $147,505

Delaware $147,099

New Hampshire $146,843

Virginia $146,271

Pennsylvania $144,600

Nevada $143,758

North Dakota $143,482

Michigan $143,046

Wisconsin $142,886

Vermont $142,567

Texas $141,681

Maine $141,623

Arizona $141,535

Ohio $141,434

Georgia $140,097

Indiana $139,429

Wyoming $139,299

Utah $139,095

Iowa $139,008

Kansas $138,311

Louisiana $138,108

North Carolina $138,035

Missouri $138,006

Florida $137,439

Montana $137,134

Nebraska $136,844

Kentucky $136,684

South Carolina $136,103

Tennessee $135,740

Idaho $135,595

New Mexico $134,534

Oklahoma $134,302

Alabama $133,445

South Dakota $132,007

Arkansas $131,222

West Virginia $130,801

Mississippi $129,538

Top Paying Cities for Clinical Data Manager IIs

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

San Jose: $183,209
San Francisco: $181,203
Oakland: $177,384

San Jose, CA $183,209

San Francisco, CA $181,203

Oakland, CA $177,384

New York, NY $167,244

Paramus, NJ $165,210

Queens Village, NY $165,203

Passaic, NJ $165,065

Bergenfield, NJ $165,052

Stamford, CT $164,733

Huntington, NY $164,673

Newark, NJ $163,600

Bridgeport, CT $163,293

Vallejo, CA $163,004

New Brunswick, NJ $162,946

Petaluma, CA $162,859

Middlesex, NJ $162,583

Somerset, NJ $162,481

Santa Cruz, CA $162,292

Boston, MA $161,406

Monterey, CA $160,896

Seattle, WA $160,564

Santa Rosa, CA $160,535

Los Angeles, CA $160,491

Juneau, AK $160,113

Washington, DC $159,954

Orange, CA $159,437

Santa Ana, CA $159,053

Long Beach, CA $158,908

Anaheim, CA $158,879

Anchorage, AK $158,806

Santa Maria, CA $158,370

Everett, WA $158,341

Danbury, CT $157,830

Bremerton, WA $157,630

Tacoma, WA $157,107

New Suffolk, NY $157,104

Sacramento, CA $157,063

Santa Barbara, CA $156,903

Trenton, NJ $156,744

San Diego, CA $156,744

Brockton, MA $156,584

Fairbanks, AK $156,228

Lompoc, CA $155,858

Lowell, MA $155,740

Ventura, CA $155,712

Nashua, NH $155,683

Stockton, CA $155,669

Modesto, CA $154,608

Poughkeepsie, NY $154,289

Olympia, WA $154,013

Kennewick, WA $154,013

New Haven, CT $153,955

Lawrence, MA $153,432

Hartford, CT $153,287

Riverside, CA $153,257

New Bedford, MA $153,112

Richland, WA $153,112

Bakersfield, CA $152,909

San Bernardino, CA $152,851

New Britain, CT $152,836

Atlantic City, NJ $152,836

New London, CT $152,778

Norwich, CT $152,735

Portsmouth, NH $152,706

Boulder, CO $152,398

Portland, OR $152,197

Worcester, MA $152,183

Minneapolis, MN $151,732

Philadelphia, PA $151,529

Honolulu, HI $151,050

Saint Paul, MN $150,980

Vineland, NJ $150,948

Providence, RI $150,527

Chicago, IL $150,105

Bellingham, WA $149,931

Springfield, MA $149,815

Baltimore, MD $149,771

Chico, CA $149,408

Pittsfield, MA $149,016

Manchester, NH $148,740

Spokane, WA $148,101

Denver, CO $148,086

Albany, NY $147,404

Troy, NY $147,346

Nassau, NY $147,190

Schenectady, NY $147,041

Wilmington, DE $146,924

Burlington, VT $146,721

Salem, OR $146,663

Portland, ME $146,213

Yakima, WA $146,067

Rochester, MN $145,617

Reno, NV $145,545

Fresno, CA $145,545

Milwaukee, WI $145,414

Detroit, MI $145,269

Ann Arbor, MI $145,244

Allentown, PA $145,225

Colorado Springs, CO $144,978

Syracuse, NY $144,905

Carson City, NV $144,905

Houston, TX $144,702

Eugene, OR $144,629

Gary, IN $144,455

Springfield, OR $144,339

Bismarck, ND $144,310

Galveston, TX $144,208

Medford, OR $143,990

Fort Collins, CO $143,932

Concord, NH $143,860

Austin, TX $143,816

Mesa, AZ $143,511

Reading, PA $143,496

Phoenix, AZ $143,482

Dallas, TX $143,438

Saint Cloud, MN $143,299

Madison, WI $143,104

Utica, NY $142,712

Rochester, NY $142,480

Des Moines, IA $142,465

Raleigh, NC $142,451

Atlanta, GA $142,233

Battle Creek, MI $142,189

Salt Lake City, UT $142,146

Lancaster, PA $141,928

Harrisburg, PA $141,724

Kansas City, MO $141,579

Champaign, IL $141,550

Kansas City, KS $141,550

Fort Worth, TX $141,535

Columbus, OH $141,511

Boca Raton, FL $141,477

Pittsburgh, PA $141,419

Richmond, VA $141,361

Indianapolis, IN $141,332

Cleveland, OH $141,318

Las Vegas, NV $141,143

Cincinnati, OH $141,143

Petersburg, VA $140,925

Huntsville, AL $140,708

Lansing, MI $140,610

Lebanon, PA $140,591

Pueblo, CO $140,577

Appleton, WI $140,533

Buffalo, NY $140,475

Dayton, OH $140,432

Racine, WI $140,403

Charlotte, NC $140,388

Saint Louis, MO $140,344

York, PA $140,257

Elkhart, IN $140,257

Gastonia, NC $140,230

Billings, MT $140,195

Beaumont, TX $140,156

Lorain, OH $140,127

Benton Harbor, MI $140,097

Toledo, OH $140,068

Binghamton, NY $139,996

Rock Hill, SC $139,981

Rockford, IL $139,909

Springfield, IL $139,851

Elyria, OH $139,836

Fargo, ND $139,836

Flagstaff, AZ $139,734

Fort Lauderdale, FL $139,647

Duluth, MN $139,560

Miami, FL $139,560

Cheyenne, WY $139,458

Grand Forks, ND $139,458

Bangor, ME $139,139

Cedar Rapids, IA $138,979

Durham, NC $138,918

Louisville, KY $138,906

Grand Rapids, MI $138,877

Hialeah, FL $138,863

Casper, WY $138,659

Scranton, PA $138,485

New Orleans, LA $138,442

Virginia Beach, VA $138,427

Akron, OH $138,354

Peoria, IL $138,166

Sarasota, FL $138,137

Nashville, TN $138,035

Omaha, NE $138,035

Green Bay, WI $138,035

Baton Rouge, LA $137,962

Charleston, SC $137,933

Jamestown, NY $137,861

Davenport, IA $137,861

Tucson, AZ $137,788

Saint Petersburg, FL $137,701

Tampa, FL $137,672

Evansville, IN $137,585

Port Arthur, TX $137,585

Bradenton, FL $137,526

Santa Fe, NM $137,265

Orlando, FL $137,004

Clearwater, FL $136,960

Canton, OH $136,655

La Crosse, WI $136,655

Albuquerque, NM $136,568

Newport News, VA $136,553

High Point, NC $136,510

Ogden, UT $136,452

Corpus Christi, TX $136,335

Norfolk, VA $136,248

Laramie, WY $136,248

Rock Island, IL $136,161

Saginaw, MI $136,132

Jacksonville, FL $136,118

Salisbury, NC $136,088

Boise, ID $136,059

Moline, IL $135,987

Fort Myers, FL $135,943

Memphis, TN $135,914

Tulsa, OK $135,842

Waterloo, IA $135,754

Spartanburg, SC $135,609

Lincoln, NE $135,537

Fort Wayne, IN $135,507

Provo, UT $135,493

Cedar Falls, IA $135,319

San Antonio, TX $135,261

Greensboro, NC $135,202

South Bend, IN $135,188

Savannah, GA $135,028

Muskegon, MI $134,970

Birmingham, AL $134,955

Winston Salem, NC $134,884

Lake Charles, LA $134,534

Anderson, IN $134,505

Lexington, KY $134,462

Augusta, GA $134,418

Greenville, SC $134,418

Lima, OH $134,302

Wichita, KS $134,287

Tuscaloosa, AL $134,287

Columbia, SC $134,157

Springfield, OH $134,128

Asheville, NC $133,895

Bloomington, IN $133,793

Knoxville, TN $133,271

Shreveport, LA $133,256

Wilmington, NC $133,067

Roanoke, VA $133,067

Topeka, KS $132,806

Frankfort, KY $132,790

Oklahoma City, OK $132,690

Chillicothe, OH $132,631

Longview, TX $132,617

Melbourne, FL $132,602

Sioux Falls, SD $132,370

Mobile, AL $132,355

Terre Haute, IN $132,297

Altoona, PA $132,210

Amarillo, TX $132,109

Killeen, TX $132,065

Fayetteville, AR $131,949

Chattanooga, TN $131,905

Sioux City, IA $131,774

Idaho Falls, ID $131,745

Lynchburg, VA $131,629

Gainesville, FL $131,440

Portsmouth, OH $131,368

Little Rock, AR $131,339

Lafayette, LA $131,281

Youngstown, OH $131,281

Daytona Beach, FL $131,193

Clarksville, TN $131,179

Pensacola, FL $131,164

Temple, TX $131,154

Hopkinsville, KY $130,729

Erie, PA $130,700

Florence, SC $130,641

Charleston, WV $130,409

Great Falls, MT $130,336

Macon, GA $130,133

Tallahassee, FL $130,119

Fayetteville, NC $130,089

Waco, TX $130,060

Helena, MT $129,959

Pine Bluff, AR $129,904

Vincennes, IN $129,726

Lubbock, TX $129,668

Alamogordo, NM $129,581

Twin Falls, ID $129,450

Rapid City, SD $129,407

Jackson, MS $129,145

Huntington, WV $129,135

Greenville, MS $129,131

Parkersburg, WV $128,983

Montgomery, AL $128,957

Wichita Falls, TX $128,811

Springfield, MO $128,811

Biloxi, MS $128,739

Monroe, LA $128,593

Johnstown, PA $128,492

Sumter, SC $128,434

Columbus, GA $128,419

Pascagoula, MS $128,143

Abilene, TX $128,143

Kingsport, TN $127,765

Albany, GA $127,765

Gulfport, MS $127,722

Alexandria, LA $127,243

Fort Smith, AR $126,879

El Paso, TX $126,487

Las Cruces, NM $125,834

Harlingen, TX $125,465

Pocatello, ID $125,441

Florence, AL $125,253

Brownsville, TX $125,223

Mcallen, TX $124,918

Dothan, AL $124,715

Columbus, MS $123,852

Altus, OK $123,175

Lawton, OK $122,899

Pierre, SD $122,376

What Skills Can Increase a Clinical Data Manager II's Salary?

Demanded Skills for the Role:

Project Management (Mentioned in 2.56% Job Postings): Project management is the application of processes, methods, skills, knowledge and experience to achieve specific project objectives according to the project acceptance criteria within agreed parameters. Project management has final deliverables that are constrained to a finite timescale and budget.
Database Design (Mentioned in 2.07% Job Postings): Overlap to row 560
Data Collection (Mentioned in 1.59% Job Postings): Data collection is the process of gathering and measuring information on targeted variables in an established system, which then enables one to answer relevant questions and evaluate outcomes. Data collection is a component of research in all fields of study including physical and social sciences, humanities, and business. While methods vary by discipline, the emphasis on ensuring accurate and honest collection remains the same. The goal for all data collection is to capture quality evidence that allows analysis to lead to the formulation of convincing and credible answers to the questions that have been posed.

See More Skills

Skills	Demand Percentage
Project Management	2.56%
Database Design	2.07%
Data Collection	1.59%

What skills can make your compensation higher?

Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Clinical Data Manager II's salary.

Biostatistics: Can increase your salary by up to 5%.
Drug Development: Can increase your salary by up to 5%.
Programming: Can increase your salary by up to 4%.

Skill	Salary	Salary % Increase
Biostatistics	$152,517	5%
Drug Development	$152,517	5%
Programming	$151,064	4%
Planning	$151,064	4%
SAS	$151,064	4%
Innovation	$151,064	4%

Get Latest Data

How Education impacts a Clinical Data Manager II's Salary?

Your level of education can impact your salary potential. While many Clinical Data Manager IIs enter the field with a Master's Degree or MBA degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Clinical Data Manager II with a Master's Degree or MBA is between $119,184 and $125,657).

Clinical Data Manager II Salaries by Degree Level

Typical Education for Clinical Data Manager II

No Diploma 7.3%

High School 7.3%

Associates 2.9%

Bachelors 49.6%

Masters 32.8%

Doctorate 7.3%

view as table

Degree Level	% of user with this level of education
No Diploma	7.3%
High School	7.3%
Associates	2.9%
Bachelors	49.6%
Masters	32.8%
Doctorate	7.3%

view as graph

Clinical Data Manager II Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Data Manager II's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on June 01, 2026

$133,294

Average $145,254/year

$164,372

$11,108

Average $12,105/month

$13,698

$2,563

Average $2,793/week

$3,161

$64

Average $70/hour

$79

	Annual Salary	Monthly Pay	Weekly Pay	Hourly Wage
75th Percentile	$164,372	$13,698	$3,161	$79
Average	$145,254	$12,105	$2,793	$70
25th Percentile	$133,294	$11,108	$2,563	$64

Salaries of jobs related to Clinical Data Manager II

Salary Trends for Clinical Data Manager II

Salaries for a Clinical Data Manager II can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $143,957 in 2023 to around $135,656 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Clinical Data Manager II salary trends, .

Average Annual Salary of Clinical Data Manager II Over Time

2022

$???

2023

$143,957

2024

$138,335

2025

$135,656

2026

$???

2027

$???

Year	Average Annual Salary
2022	View More
2023	$143,957
2024	$138,335
2025	$135,656
2026	View More
2027	View More

Most common benefits for Clinical Data Manager II

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Where Does Our Salary Data Come From?

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