upper level job

Clinical Research Project Manager II Salary in the United States

How much does a Clinical Research Project Manager II make in the United States?

As of July 01, 2026, the average salary for a Clinical Research Project Manager II in the United States is $86,101 per year, which breaks down to an hourly rate of $41.

However, a Clinical Research Project Manager II's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $102,561
  • Majority Range (25th-75th percentile): $77,597 to $94,717
  • Entry-Level (10th percentile): $69,855
Compensation Planning
Develop a Job Description
Pay Equity
2026 Compensation Trend
Recruit with AI
AI-Powered Talent
Salary Salary + Bonus Benefits
Paid Annually Paid Monthly Paid Semimonthly Paid Biweekly Paid Weekly Paid Hourly
View as table View as graph 25% $77,597 10% $69,855 90% $102,561 75% $94,717 $86,101 50%(Median) Didn’t find job title? Click

Clinical Research Project Manager II Salaries by Percentile

Annual
Salary		 Monthly
Pay		 Weekly
Pay		 Hourly
Wage
75th Percentile $94,717 $7,893 $1,821 $46
Average $86,101 $7,175 $1,656 $41
25th Percentile $77,597 $6,466 $1,492 $37
Select State
Select City
Choose Similar Job
Choose Category
Cost of Living
Hourly Wages
See it in Action

Key Factors That Influence Clinical Research Project Manager II Salaries

A Clinical Research Project Manager II's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.

How Experience Level Affects Clinical Research Project Manager Salaries?

Experience is a primary driver of a Clinical Research Project Manager II's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Research Project Manager I (0-2 years): $62,898
  • Clinical Research Project Manager II (2-4 years): $86,101
  • Clinical Research Project Manager III (4-7 years): $100,836
  • Clinical Research Project Manager IV (7+ years): $114,706
  • Clinical Research Project Manager V (7-10 years): $141,634
Job Role Years of Experience Average Salary
Clinical Research Project Manager I0-2 years$62,898
Clinical Research Project Manager II2-4 years$86,101
Clinical Research Project Manager III4-7 years$100,836
Clinical Research Project Manager IV7+ years$114,706
Clinical Research Project Manager V7-10 years$141,634
$62,898 Clinical ...
$86,101 Clinical ...
$100,836 Clinical ...
$114,706 Clinical ...
$141,634 Clinical ...
View as Table
View as Graph

What Am I Worth?

Top Paying Cities for Clinical Research Project Manager IIs

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $108,599
  • San Francisco: $107,410
  • Oakland: $105,147

Clinical Research Project Manager II Salary by Company Size: Startups vs. Enterprise

Clinical Research Project Manager II salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $97,646. While startup companies pay approximate $82,838.

Clinical Research Project Manager II Salary by Company Size

Company Size Employees Average Salary
Startup1~50$82,838
Growth Stage51~500$87,542
Established501~5000$94,362
Enterprise5000+$97,646

Clinical Research Project Manager II Salary by Industry: Top Paying Sectors

For Clinical Research Project Manager II roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Chemicals sectors offer the strongest compensation, at 20% above the average. In contrast, Clinical Research Project Manager positions in Biotechnology or Edu., Gov't. & Nonprofit typically offer lower base pay, as these industries often view Clinical Research Project Manager II as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Research Project Manager II

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$103,321$50.020%
Chemicals$94,711$46.010%

Clinical Research Project Manager II Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Research Project Manager II's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

  • Hourly
  • Monthly
  • Weekly
  • Yearly
  • Table View
Last Updated on July 01, 2026
$77,597
Average $86,101/year
$94,717
$6,466
Average $7,175/month
$7,893
$1,492
Average $1,656/week
$1,821
$37
Average $41/hour
$46
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $94,717 $7,893 $1,821 $46
Average $86,101 $7,175 $1,656 $41
25th Percentile $77,597 $6,466 $1,492 $37

Clinical Research Project Manager II Salary Growth & Career Path

Clinical Research Project Manager II
Clinical Research Project Manager III
VP of Clinical Research Project Management

For a Clinical Research Project Manager II, the most direct path to higher earnings is advancing to the Clinical Research Project Manager III role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $100,836 - a projected growth of 17% over your current level.

Salaries of jobs related to Clinical Research Project Manager II

Most common benefits for Clinical Research Project Manager II

Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
For Employers

If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution.

Compensation Planning

Common company salaries for Clinical Research Project Manager II

Here are companies hiring for Clinical Research Project Manager II and their salaries, click below for more details.

Find Your Next Clinical Research Project Manager II Job

Ready to take the next step in your career? Browse thousands of current Clinical Research Project Manager II job openings on our job board. Use the search bar below to find your perfect match.

United States
For Employees

Get a Salary Increase

Analyze the market and your qualifications to negotiate your salary with confidence.

Search Job Openings

Search thousands of open positions to find your next opportunity.

For Employers

Adjust Employee Salary

Individualize employee pay based on unique job requirements and personal qualifications.

Price My Industry Jobs

Get the latest market price for benchmark jobs and jobs in your industry.

FAQ about Clinical Research Project Manager II

1. Where can a Clinical Research Project Manager II earn the most?

A Clinical Research Project Manager II's earning potential can vary widely depending on several factors, including location, industry, experience, education, and the specific employer. According to the latest salary data by Salary.com, a Clinical Research Project Manager II earns the most in San Jose, CA, where the annual salary of a Clinical Research Project Manager II is $108,599.

2. What is the highest pay for Clinical Research Project Manager II?

The highest pay for Clinical Research Project Manager II is $102,561.

3. What is the lowest pay for Clinical Research Project Manager II?

The lowest pay for Clinical Research Project Manager II is $69,855.

4. What are the responsibilities of Clinical Research Project Manager II?

Manages and oversees all aspects of clinical research projects. Ensures projects are timely, are evaluating accurate data, and are producing precise results. Plans, directs, creates, and communicates the study timeline. Develops detailed project plans, and monitors project milestones against performance indicators. Ensures the project is planned and conducted in accordance with all applicable regulations, standard operating procedures, and good clinical practices (GCP). Manages risk assessment and mitigation. Generates reports to provide periodic status updates. Requires a bachelor's degree. Typically reports to a manager. Occasionally directed in several aspects of the work. Gaining exposure to some of the complex tasks within the job function. Typically requires 2-4 years of related experience.

5. What industry pays the highest salary for Clinical Research Project Manager II?

The Healthcare industry offers the highest average compensation for Clinical Research Project Manager II roles, with salaries approximately 20% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

Are you an HR manager or compensation specialist?

Salary.com's CompAnalyst platform offers:

  • Detailed skills and competency reports for specific positions
  • Job and employee pricing reports
  • Compensation data tools, salary structures, surveys and benchmarks.
Learn about CompAnalyst
lower level job