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Bioinformatics Software Engineer Salary in the United States

How much does a Bioinformatics Software Engineer make in the United States?

As of August 01, 2026, the average salary for a Bioinformatics Software Engineer in the United States is $100,488 per year, which breaks down to an hourly rate of $48.

However, a Bioinformatics Software Engineer's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $118,754
  • Majority Range (25th-75th percentile): $91,338 to $110,049
  • Entry-Level (10th percentile): $83,007
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Paid Annually Paid Monthly Paid Semimonthly Paid Biweekly Paid Weekly Paid Hourly
View as table View as graph 25% $91,338 10% $83,007 90% $118,754 75% $110,049 $100,488 50%(Median) Didn’t find job title? Click

Bioinformatics Software Engineer Salaries by Percentile

Annual
Salary		 Monthly
Pay		 Weekly
Pay		 Hourly
Wage
75th Percentile $110,049 $9,171 $2,116 $53
Average $100,488 $8,374 $1,932 $48
25th Percentile $91,338 $7,611 $1,756 $44
Check out Bioinformatics Software Engineer Job Openings in the United States
Software Engineer

Loop - Columbus, OH

Software Engineer

Liberty Information Technology Limited - Columbus, OH

Software Engineer

Donato Technologies Inc - Columbus, OH

Software Engineer

Thomas & Reed, LLC - Columbus, OH

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Key Factors That Influence Bioinformatics Software Engineer Salaries

A Bioinformatics Software Engineer's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

Top Paying Cities for Bioinformatics Software Engineers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $126,746
  • San Francisco: $125,358
  • Oakland: $122,716

What Skills Can Increase a Bioinformatics Software Engineer's Salary?

Demanded Skills for the Role:

  • Planning (Mentioned in 9.09% Job Postings): An act or process of making or carrying out plans. Establishment of goals, policies, and procedures for a social or economic unit city planning business planning.
  • Economics (Mentioned in 2.32% Job Postings): Economics is a social science that focuses on the production, distribution, and consumption of goods and services, and analyzes the choices that individuals, businesses, governments, and nations make to allocate resources.
  • Purchasing (Mentioned in 1.94% Job Postings): Purchasing refers to a business or organization attempting to acquire goods or services to accomplish its goals. Although there are several organizations that attempt to set standards in the purchasing process, processes can vary greatly between organizations. Typically the word “purchasing” is not used interchangeably with the word “procurement”, since procurement typically includes expediting, supplier quality, and transportation and logistics (T&L) in addition to purchasing.
See More Skills
Skills Demand Percentage
Planning 9.09%
Economics 2.32%
Purchasing 1.94%
What skills can make your compensation higher?
Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Bioinformatics Software Engineer's salary.
  • Innovation: Can increase your salary by up to 7%.
  • Budgeting: Can increase your salary by up to 6%.
  • Collaboration: Can increase your salary by up to 5%.
Skill Salary Salary % Increase
Innovation
 $107,522
7%
Budgeting
 $106,517
6%
Collaboration
 $105,512
5%
Analysis
 $105,512
5%
Coaching
 $104,508
4%
Coordination
 $104,508
4%
Get Latest Data

Bioinformatics Software Engineer Salary by Industry: Top Paying Sectors

For Bioinformatics Software Engineer roles, the industry you choose can impact your earning potential by as much as 50% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Business Services, offers compensation 20% above the average. Conversely, Bioinformatics Software Engineer positions in Healthcare typically offer lower base pay, as this sector often view Bioinformatics Software Engineer as a support function rather than a direct revenue driver.

The top paying industries for a Bioinformatics Software Engineer

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Business Services$120,586$58.020%
Edu., Gov't. & Nonprofit$110,537$53.010%

How Education impacts a Bioinformatics Software Engineer's Salary?

Your level of education can impact your salary potential. While many Bioinformatics Software Engineers enter the field with a High School Diploma or Technical Certificate degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Bioinformatics Software Engineer with a High School Diploma or Technical Certificate is between $98,881 and $106,777).

Bioinformatics Software Engineer Salaries by Degree Level

Typical Education for Bioinformatics Software Engineer
Degree Level % of user with this level of education
No Diploma 13.3%
High School 13.3%
Associates 5.0%
Bachelors 25.0%
Masters 56.7%
Doctorate 0.0%
view as graph

Bioinformatics Software Engineer Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Bioinformatics Software Engineer's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

  • Hourly
  • Monthly
  • Weekly
  • Yearly
  • Table View
Last Updated on August 01, 2026
$91,338
Average $100,488/year
$110,049
$7,611
Average $8,374/month
$9,171
$1,756
Average $1,932/week
$2,116
$44
Average $48/hour
$53
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $110,049 $9,171 $2,116 $53
Average $100,488 $8,374 $1,932 $48
25th Percentile $91,338 $7,611 $1,756 $44

Salaries of jobs related to Bioinformatics Software Engineer

Salary Trends for Bioinformatics Software Engineer

Salaries for a Bioinformatics Software Engineer can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $133,498 in 2023 to around $132,046 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Bioinformatics Software Engineer salary trends, .

Average Annual Salary of Bioinformatics Software Engineer Over Time

2022
$???
2023
$133,498
2024
$134,505
2025
$132,046
2026
$???
2027
$???
Year Average Annual Salary
2022
View More
2023 $133,498
2024 $134,505
2025 $132,046
2026
View More
2027
View More

Most common benefits for Bioinformatics Software Engineer

Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
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Common company salaries for Bioinformatics Software Engineer

Here are companies hiring for Bioinformatics Software Engineer and their salaries, click below for more details.

Find Your Next Bioinformatics Software Engineer Job

Ready to take the next step in your career? Browse thousands of current Bioinformatics Software Engineer job openings on our job board. Use the search bar below to find your perfect match.

United States

  • Impact.com

    Columbus, OH

    Senior Software Engineer

    Impact.com | Columbus, OH

    Job Description. Job Description. The Company. impact.com is the world's leading commerce partnership marketing platform, transforming the way businesses g... more

    4 Days Ago

  • Jumpmind, Inc.

    Columbus, OH

    Senior Software Engineer

    Jumpmind, Inc. | Columbus, OH

    Job Description. Job Description. Columbus, OH, US (hybrid work). Job Description. Jumpmind is looking for a Senior Software Engineer, who is passionate ab... more

    5 Days Ago

  • giftHEALTH Inc

    Columbus, OH

    Senior Software Engineer

    giftHEALTH Inc | Columbus, OH

    Job Description. Job Description. Description. About Us. At Gifthealth, we're revolutionizing the way people experience healthcare by simplifying the proce... more

    5 Days Ago

  • Staffing the Universe

    Columbus, OH

    Senior Software Engineer

    Staffing the Universe | Columbus, OH

    Senior Software Engineer (TACL HPE Nonstop)Location:Jersey City, NJ OR Tampa, FL OR Plano, TX OR Columbus, OHDuration:12Months (Possibility of Extension)Jo... more

    6 Days Ago

  • SynergisticIT

    Columbus, OH

    Junior Software Engineer

    SynergisticIT | Columbus, OH

    Synergisticit Job OpportunitySynergisticIT for the past 15 years has helped jobseekers differentiate themselves by providing the clients with candidates wh... more

    6 Days Ago

  • SynergisticIT

    Columbus, OH

    Junior Software Engineer

    SynergisticIT | Columbus, OH

    Synergisticit Job OpportunityFor more than 12 years Synergisticit has helped jobseekers stand out from other jobseekers by providing candidates the requisi... more

    6 Days Ago

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FAQ about Bioinformatics Software Engineer

1. What industry pays the highest salary for Bioinformatics Software Engineer?

The Business Services industry offers the highest average compensation for Bioinformatics Software Engineer roles, with salaries approximately 20% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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