As of February 01, 2026, the average annual salary for Computational Biologist in the US is $63,104, equivalent to $30 per hour, $1,214 weekly, or $5,259 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Computational Biologist in cities like Santa Clara, San Jose, and Fremont.
Annually Salaries for Computational Biologist in the US vary widely, spanning from $49,724 to $73,984. Most professionals fall between the 25th percentile ($56,101) and 75th percentile ($68,799), while top earners (90th percentile) make $73,984 per year. This $12,698 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Microbiology, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, District of Columbia Computational Biologist often earn 10.7% above national averages due to demand from Fortune 71 companies and industry startups. Professionals are advised to focus on high-growth sectors like to offset market challenges.
