As of February 01, 2026, the average annual salary for Computational Biologist in California is $69,604, equivalent to $33 per hour, $1,339 weekly, or $5,800 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Computational Biologist in cities like Santa Clara, San Jose, and Fremont.
Annually Salaries for Computational Biologist in California vary widely, spanning from $54,846 to $81,604. Most professionals fall between the 25th percentile ($61,879) and 75th percentile ($75,885), while top earners (90th percentile) make $81,604 per year. This $14,006 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Microbiology, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, California Computational Biologist often earn 10.3% higher than national averages due to demand from Fortune 71 companies. However, California currently ranks 2 nationwide for Computational Biologist job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.