As of October 01, 2026, the average annual salary for general surgery nurse practitioner in California is $138,229, equivalent to $66 per hour, $2,658 weekly, or $11,519 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for general surgery nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for general surgery nurse practitioner in California vary widely, spanning from $124,017 to $154,895. Most professionals fall between the 25th percentile ($130,790) and 75th percentile ($146,953), while top earners (90th percentile) make $154,895 per year. This $16,163 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, California general surgery nurse practitioner often earn 10.3% higher than national averages due to demand from Fortune 65 companies. However, California currently ranks 2 nationwide for general surgery nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
general surgery nurse practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile general surgery nurse practitioner Salary $124,017 CA October 01, 2026
25th Percentile general surgery nurse practitioner Salary $130,790 CA October 01, 2026
50th Percentile general surgery nurse practitioner Salary $138,229 CA October 01, 2026
75th Percentile general surgery nurse practitioner Salary $146,953 CA October 01, 2026
90th Percentile general surgery nurse practitioner Salary $154,895 CA October 01, 2026
25% $130,790 10% $124,017 90% $154,895 75% $146,953 $138,229 50%(Median) Didn’t find job title? Click
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Check out general surgery nurse practitioner jobs in California

Nurse Practitioner Cardiac Surgery

Common Spirit Health - Sacramento, CA

Nurse Practitioner 2, Surgery - Variable

University of California - Irvine, CA

Nurse Practitioner, Surgery - (Per Diem)

University of California - Irvine, CA

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What is A general surgery nurse practitioner ?

A general surgery nurse practitioner (NP) specializes in providing comprehensive care to surgical patients. Responsibilities include conducting pre-operative assessments, assisting in surgical procedures, managing post-operative care, and educating patients about recovery processes. NPs in this field collaborate with surgeons and other healthcare professionals to ensure optimal patient outcomes. The salary for a general surgery nurse practitioner varies based on factors such as geographic location, years of experience, and the type of healthcare facility. On average, salaries range from $90,...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Coachella, CA Avg. Salary $146,513 Date Updated October 01, 2026
Location Acampo, CA Avg. Salary $155,761 Date Updated October 01, 2026
Location Acton, CA Avg. Salary $156,170 Date Updated October 01, 2026
Location Adelanto, CA Avg. Salary $151,240 Date Updated October 01, 2026
Location Adin, CA Avg. Salary $147,766 Date Updated October 01, 2026
Location Agoura Hills, CA Avg. Salary $155,774 Date Updated October 01, 2026
Location Aguanga, CA Avg. Salary $150,003 Date Updated October 01, 2026
Location Ahwahnee, CA Avg. Salary $146,887 Date Updated October 01, 2026
Location Alameda, CA Avg. Salary $177,410 Date Updated October 01, 2026
Location Alamo, CA Avg. Salary $172,522 Date Updated October 01, 2026
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