As of August 01, 2026, the average annual salary for Internal Medicine Nurse in California is $105,703, equivalent to $51 per hour, $2,033 weekly, or $8,809 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Internal Medicine Nurse in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Internal Medicine Nurse in California vary widely, spanning from $92,365 to $124,385. Most professionals fall between the 25th percentile ($98,721) and 75th percentile ($115,482), while top earners (90th percentile) make $124,385 per year. This $16,761 pay gap underscores opportunities for salary growth through certifications, specialized skills like Planning or Nursing Process, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, California Internal Medicine Nurse often earn 10.3% higher than national averages due to demand from Fortune 56 companies. However, California currently ranks 2 nationwide for Internal Medicine Nurse job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Internal Medicine Nurse Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Internal Medicine Nurse Salary $92,365 CA August 01, 2026
25th Percentile Internal Medicine Nurse Salary $98,721 CA August 01, 2026
50th Percentile Internal Medicine Nurse Salary $105,703 CA August 01, 2026
75th Percentile Internal Medicine Nurse Salary $115,482 CA August 01, 2026
90th Percentile Internal Medicine Nurse Salary $124,385 CA August 01, 2026
25% $98,721 10% $92,365 90% $124,385 75% $115,482 $105,703 50%(Median) Didn’t find job title? Click
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Internal Medicine Nurse Practitioner

Provider Healthcare - San Diego, CA

Internal Medicine Nurse Practitioner

Alignment Health - Stockton, CA

Internal Medicine Nurse Practitioner

UC Davis Health System - Sacramento, CA

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What is An Internal Medicine Nurse ?

The salary for an Internal Medicine Nurse varies based on factors such as experience, location, and the healthcare facility. On average, these professionals earn between $70,000 and $100,000 annually. Entry-level positions may start around $60,000, while those with advanced certifications or extensive experience can exceed $100,000. Geographic location plays a significant role, with urban areas typically offering higher salaries due to the cost of living. Additionally, specialized skills and certifications can enhance earning potential. Benefits such as health insurance, retirement plans, and ...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Coachella, CA Avg. Salary $106,110 Date Updated August 01, 2026
Location Acampo, CA Avg. Salary $112,808 Date Updated August 01, 2026
Location Acton, CA Avg. Salary $113,104 Date Updated August 01, 2026
Location Adelanto, CA Avg. Salary $109,534 Date Updated August 01, 2026
Location Adin, CA Avg. Salary $107,018 Date Updated August 01, 2026
Location Agoura Hills, CA Avg. Salary $112,817 Date Updated August 01, 2026
Location Aguanga, CA Avg. Salary $108,638 Date Updated August 01, 2026
Location Ahwahnee, CA Avg. Salary $106,381 Date Updated August 01, 2026
Location Alameda, CA Avg. Salary $128,487 Date Updated August 01, 2026
Location Alamo, CA Avg. Salary $124,947 Date Updated August 01, 2026
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