As of January 01, 2026, the average annual salary for Internal Medicine Nurse in the US is $95,906, equivalent to $46 per hour, $1,844 weekly, or $7,992 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Internal Medicine Nurse in cities like Santa Clara, San Jose, and Fremont.
Annually Salaries for Internal Medicine Nurse in the US vary widely, spanning from $83,899 to $112,961. Most professionals fall between the 25th percentile ($89,621) and 75th percentile ($104,834), while top earners (90th percentile) make $112,961 per year. This $15,213 pay gap underscores opportunities for salary growth through certifications, specialized skills like Planning or Nursing Process, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, District of Columbia Internal Medicine Nurse often earn 10.7% above national averages due to demand from Fortune 56 companies and industry startups. Professionals are advised to focus on high-growth sectors like to offset market challenges.
