As of September 01, 2026, the average annual salary for Lead Medical Assistant in North Carolina is $111,812, equivalent to $54 per hour, $2,150 weekly, or $9,318 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Lead Medical Assistant in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Lead Medical Assistant in North Carolina vary widely, spanning from $88,197 to $134,418. Most professionals fall between the 25th percentile ($99,451) and 75th percentile ($123,645), while top earners (90th percentile) make $134,418 per year. This $24,194 pay gap underscores opportunities for salary growth through certifications, specialized skills like Leadership or Clinical Operations, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, North Carolina Lead Medical Assistant often earn 5.0% lower than national averages due to demand from Fortune 34 companies. However, North Carolina currently ranks 36 nationwide for Lead Medical Assistant job salary. Professionals are advised to focus on high-growth sectors like Edu., Gov't. & Nonprofit to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Lead Medical Assistant Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Lead Medical Assistant Salary $88,197 NC September 01, 2026
25th Percentile Lead Medical Assistant Salary $99,451 NC September 01, 2026
50th Percentile Lead Medical Assistant Salary $111,812 NC September 01, 2026
75th Percentile Lead Medical Assistant Salary $123,645 NC September 01, 2026
90th Percentile Lead Medical Assistant Salary $134,418 NC September 01, 2026
25% $99,451 10% $88,197 90% $134,418 75% $123,645 $111,812 50%(Median) Didn’t find job title? Click
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Check out Lead Medical Assistant jobs in North Carolina

Lead Medical Assistant

Appalachian Mountain Community Health Centers - Sylva, NC

LEAD MEDICAL SUPPORT ASSISTANT

USA Government Jobs - Greenville, NC

Lead Medical Support Assistant

USA Government Jobs - Asheville, NC

Lead Certified Medical Assistant

Cabarrus Rowan Community Health Center - Salisbury, NC

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Lead Medical Assistant

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Location Avg. Salary Date Updated
Location Aberdeen, NC Avg. Salary $99,084 Date Updated September 01, 2026
Location Advance, NC Avg. Salary $101,155 Date Updated September 01, 2026
Location Ahoskie, NC Avg. Salary $99,208 Date Updated September 01, 2026
Location Alamance, NC Avg. Salary $101,426 Date Updated September 01, 2026
Location Albemarle, NC Avg. Salary $101,239 Date Updated September 01, 2026
Location Albertson, NC Avg. Salary $98,468 Date Updated September 01, 2026
Location Alexander, NC Avg. Salary $100,523 Date Updated September 01, 2026
Location Alexis, NC Avg. Salary $104,433 Date Updated September 01, 2026
Location Alliance, NC Avg. Salary $98,176 Date Updated September 01, 2026
Location Almond, NC Avg. Salary $98,869 Date Updated September 01, 2026
Job Openings for Lead Medical Assistant in North Carolina

Career Path for this job

  1. Down a level:

    Clinic Manager I

    3 + years experience
    Bachelor's Degree

  2. This Job:

    Lead Medical Assistant

    3 - 5 years experience
    Bachelor's Degree

  3. Up a level:

    Clinic Manager III

    5 + years experience
    Bachelor's Degree

Recently searched related titles: Clinic Site Manager, Clinical Site Manager, Clinical Team Lead

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