As of August 01, 2026, the average annual salary for nurse informatics in Pennsylvania is $109,339, equivalent to $53 per hour, $2,103 weekly, or $9,112 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for nurse informatics in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for nurse informatics in Pennsylvania vary widely, spanning from $90,618 to $127,213. Most professionals fall between the 25th percentile ($99,540) and 75th percentile ($118,695), while top earners (90th percentile) make $127,213 per year. This $19,155 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Integrated Care, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, Pennsylvania nurse informatics often earn 0.5% lower than national averages due to demand from Fortune 40 companies. However, Pennsylvania currently ranks 19 nationwide for nurse informatics job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
nurse informatics Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile nurse informatics Salary $90,618 PA August 01, 2026
25th Percentile nurse informatics Salary $99,540 PA August 01, 2026
50th Percentile nurse informatics Salary $109,339 PA August 01, 2026
75th Percentile nurse informatics Salary $118,695 PA August 01, 2026
90th Percentile nurse informatics Salary $127,213 PA August 01, 2026
25% $99,540 10% $90,618 90% $127,213 75% $118,695 $109,339 50%(Median) Didn’t find job title? Click
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Check out nurse informatics jobs in Pennsylvania

Informatics Nurse Practitioner

Jefferson Health - Abington, PA

Nurse Practitioner

Woundara Wound Care - FORT WAYNE, IN

Nurse Practitioner

Desert Sage Health Centers - MOUNTAIN HOME, ID

REGISTERED NURSE

Siouxland Community Health Center - SIOUX CITY, IA

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What is A nurse informatics ?

Nurse informatics professionals play a crucial role in integrating nursing science with information management and analytical sciences to enhance healthcare outcomes. They are responsible for managing and analyzing health information systems, ensuring data accuracy, and improving patient care through technology. Typical duties include collaborating with healthcare teams to implement electronic health records (EHR), training staff on new systems, and evaluating the effectiveness of informatics solutions. Salaries for nurse informatics specialists can vary widely based on factors such as educat...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Stroudsburg, PA Avg. Salary $107,945 Date Updated August 01, 2026
Location Aaronsburg, PA Avg. Salary $100,528 Date Updated August 01, 2026
Location Abbottstown, PA Avg. Salary $103,556 Date Updated August 01, 2026
Location Abington, PA Avg. Salary $111,787 Date Updated August 01, 2026
Location Ackermanville, PA Avg. Salary $109,730 Date Updated August 01, 2026
Location Acme, PA Avg. Salary $99,616 Date Updated August 01, 2026
Location Acosta, PA Avg. Salary $96,272 Date Updated August 01, 2026
Location Adah, PA Avg. Salary $101,837 Date Updated August 01, 2026
Location Adamsburg, PA Avg. Salary $102,786 Date Updated August 01, 2026
Location Adamstown, PA Avg. Salary $105,441 Date Updated August 01, 2026
Job Openings for nurse informatics in Pennsylvania

Jobs with a similar salary range to nurse informatics : Informaticist, Rn Clinical Data Abstractor, Informatics Analyst