As of August 01, 2026, the average annual salary for nurse informatics in South Dakota is $99,817, equivalent to $48 per hour, $1,920 weekly, or $8,318 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for nurse informatics in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for nurse informatics in South Dakota vary widely, spanning from $82,725 to $116,134. Most professionals fall between the 25th percentile ($90,871) and 75th percentile ($108,358), while top earners (90th percentile) make $116,134 per year. This $17,487 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Integrated Care, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, South Dakota nurse informatics often earn 9.1% lower than national averages due to demand from Fortune 40 companies. However, South Dakota currently ranks 48 nationwide for nurse informatics job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
nurse informatics Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile nurse informatics Salary $82,725 SD August 01, 2026
25th Percentile nurse informatics Salary $90,871 SD August 01, 2026
50th Percentile nurse informatics Salary $99,817 SD August 01, 2026
75th Percentile nurse informatics Salary $108,358 SD August 01, 2026
90th Percentile nurse informatics Salary $116,134 SD August 01, 2026
25% $90,871 10% $82,725 90% $116,134 75% $108,358 $99,817 50%(Median) Didn’t find job title? Click
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Check out nurse informatics jobs in South Dakota

Nurse Practitioner

Woundara Wound Care - FORT WAYNE, IN

Nurse Practitioner

Desert Sage Health Centers - MOUNTAIN HOME, ID

REGISTERED NURSE

Siouxland Community Health Center - SIOUX CITY, IA

Registered Nurse

Richmond Healthcare & Rehab Center - RICHMOND, KS

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What is A nurse informatics ?

Nurse informatics professionals play a crucial role in integrating nursing science with information management and analytical sciences to enhance healthcare outcomes. They are responsible for managing and analyzing health information systems, ensuring data accuracy, and improving patient care through technology. Typical duties include collaborating with healthcare teams to implement electronic health records (EHR), training staff on new systems, and evaluating the effectiveness of informatics solutions. Salaries for nurse informatics specialists can vary widely based on factors such as educat...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Deadwood, SD Avg. Salary $96,501 Date Updated August 01, 2026
Location Pierre, SD Avg. Salary $90,061 Date Updated August 01, 2026
Location Watertown, SD Avg. Salary $99,054 Date Updated August 01, 2026
Location Aberdeen, SD Avg. Salary $98,887 Date Updated August 01, 2026
Location Agar, SD Avg. Salary $92,404 Date Updated August 01, 2026
Location Akaska, SD Avg. Salary $98,004 Date Updated August 01, 2026
Location Alcester, SD Avg. Salary $98,161 Date Updated August 01, 2026
Location Alexandria, SD Avg. Salary $98,492 Date Updated August 01, 2026
Location Allen, SD Avg. Salary $97,836 Date Updated August 01, 2026
Location Alpena, SD Avg. Salary $98,659 Date Updated August 01, 2026
Job Openings for nurse informatics in South Dakota

Jobs with a similar salary range to nurse informatics : Informaticist, Rn Clinical Data Abstractor, Informatics Analyst