As of April 01, 2026, the average annual salary for nurse informatics in South Dakota is $99,769, equivalent to $48 per hour, $1,919 weekly, or $8,314 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for nurse informatics in cities like Santa Clara, San Jose, and Fremont.

Annually Salaries for nurse informatics in South Dakota vary widely, spanning from $82,776 to $116,189. Most professionals fall between the 25th percentile ($90,874) and 75th percentile ($108,364), while top earners (90th percentile) make $116,189 per year. This $17,490 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Integrated Care, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, South Dakota nurse informatics often earn 9.1% lower than national averages due to demand from Fortune 40 companies. However, South Dakota currently ranks 48 nationwide for nurse informatics job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
nurse informatics Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile nurse informatics Salary $82,776 SD April 01, 2026
25th Percentile nurse informatics Salary $90,874 SD April 01, 2026
50th Percentile nurse informatics Salary $99,769 SD April 01, 2026
75th Percentile nurse informatics Salary $108,364 SD April 01, 2026
90th Percentile nurse informatics Salary $116,189 SD April 01, 2026
25% $90,874 10% $82,776 90% $116,189 75% $108,364 $99,769 50%(Median) Didn’t find job title? Click
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Check out nurse informatics jobs in South Dakota

Registered Nurse

Amberwell Health Hiawatha - HIAWATHA, KS

Registered Nurse (RN)

Adept Nursing & Rehab of Sutherland - SUTHERLAND, NE

Registered Nurse RN

Flint Hills Care & Rehab Center - EMPORIA, KS

Registered Nurse (RN)

The Emeralds at Faribault - FARIBAULT, MN

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What is A nurse informatics ?

Nurse informatics professionals play a crucial role in integrating nursing science with information management and analytical sciences to enhance healthcare outcomes. They are responsible for managing and analyzing health information systems, ensuring data accuracy, and improving patient care through technology. Typical duties include collaborating with healthcare teams to implement electronic health records (EHR), training staff on new systems, and evaluating the effectiveness of informatics solutions. Salaries for nurse informatics specialists can vary widely based on factors such as educat...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Deadwood, SD Avg. Salary $91,651 Date Updated April 01, 2026
Location Pierre, SD Avg. Salary $88,257 Date Updated April 01, 2026
Location Watertown, SD Avg. Salary $93,516 Date Updated April 01, 2026
Location Aberdeen, SD Avg. Salary $86,685 Date Updated April 01, 2026
Location Agar, SD Avg. Salary $86,685 Date Updated April 01, 2026
Location Akaska, SD Avg. Salary $86,685 Date Updated April 01, 2026
Location Alcester, SD Avg. Salary $93,379 Date Updated April 01, 2026
Location Alexandria, SD Avg. Salary $93,516 Date Updated April 01, 2026
Location Allen, SD Avg. Salary $91,651 Date Updated April 01, 2026
Location Alpena, SD Avg. Salary $90,100 Date Updated April 01, 2026
Job Openings for nurse informatics in South Dakota

Jobs with a similar salary range to nurse informatics : Informaticist, Rn Clinical Data Abstractor, Informatics Analyst