As of February 01, 2026, the average annual salary for Python Developer in Missouri is $62,536, equivalent to $30 per hour, $1,203 weekly, or $5,211 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Python Developer in cities like Santa Clara, San Jose, and Fremont.
Annually Salaries for Python Developer in Missouri vary widely, spanning from $55,612 to $75,320. Most professionals fall between the 25th percentile ($58,912) and 75th percentile ($69,228), while top earners (90th percentile) make $75,320 per year. This $10,316 pay gap underscores opportunities for salary growth through certifications, specialized skills like Commitment or API, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, Missouri Python Developer often earn 5.0% lower than national averages due to demand from Fortune 58 companies. However, Missouri currently ranks 37 nationwide for Python Developer job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.
