As of March 01, 2026, the average annual salary for Python Developer in Saint Louis, MO is $63,597, equivalent to $31 per hour, $1,223 weekly, or $5,300 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Python Developer in cities like Santa Clara, San Jose, and Fremont.

Annually Salaries for Python Developer in Saint Louis, MO vary widely, spanning from $56,556 to $76,599. Most professionals fall between the 25th percentile ($59,912) and 75th percentile ($70,403), while top earners (90th percentile) make $76,599 per year. This $10,491 pay gap underscores opportunities for salary growth through certifications, specialized skills like Commitment or API, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, Saint Louis Python Developer often earn 1.7% lower than national averages. However, Saint Louis currently ranks 497 statewide for Python Developer job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Python Developer Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Python Developer Salary $56,556 Saint Louis, MO March 01, 2026
25th Percentile Python Developer Salary $59,912 Saint Louis, MO March 01, 2026
50th Percentile Python Developer Salary $63,597 Saint Louis, MO March 01, 2026
75th Percentile Python Developer Salary $70,403 Saint Louis, MO March 01, 2026
90th Percentile Python Developer Salary $76,599 Saint Louis, MO March 01, 2026
25% $59,912 10% $56,556 90% $76,599 75% $70,403 $63,597 50%(Median) Didn’t find job title? Click
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Check out Python Developer jobs in Saint Louis, Missouri

Python Developer

TechDigital Group - California, MO

Python Developer - AI Training

Data Freelance Hub - California, MO

Lead Python Developer

Robotics Prcocess Automation, LLC - Kansas City, MO

Senior Python Developer

Crosslynx US LLC - California, MO

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Python Developer

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Job Openings for Python Developer in Saint Louis, MO

Career Path for this job

  1. This Job:

    Python Developer

    0 - 2 years experience
    Bachelor's Degree

  2. Up a level:

    Frontend Developer II

    2 - 4 years experience
    Bachelor's Degree

Understand the total compensation opportunity for a Python Developer, base salary plus other pay elements

Average Base Salary

Core compensation

 
 
 
59912
70403
63597

Average Total Cash Compensation

Includes base and annual incentives

 
 
 
64045
75056
70362
These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of Python Developer in Saint Louis, MO. The base salary for Python Developer ranges from $59,912 to $70,403 with the average base salary of $63,597. The total cash compensation, which includes base, and annual incentives, can vary anywhere from $64,045 to $75,056 with the average total cash compensation of $70,362.

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59912
70403

 

About Saint Louis, Missouri    St. Louis (/seɪnt ˈluːɪs/) is an independent city and major inland port in the U.S. state of Missouri. It is situated along the western bank of the Mi....More

Saint Louis, Missouri  area prices were up 0.7% from a year ago

Python Developer Salary in popular cities: Kansas CitySpringfieldIndependence

Skills associated with Python Developer: Create, RISK

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