As of February 01, 2026, the average annual salary for Python Developer in Saint Louis, MO is $63,595, equivalent to $31 per hour, $1,223 weekly, or $5,300 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Python Developer in cities like Santa Clara, San Jose, and Fremont.
Annually Salaries for Python Developer in Saint Louis, MO vary widely, spanning from $56,555 to $76,597. Most professionals fall between the 25th percentile ($59,910) and 75th percentile ($70,401), while top earners (90th percentile) make $76,597 per year. This $10,491 pay gap underscores opportunities for salary growth through certifications, specialized skills like Commitment or API, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, Saint Louis Python Developer often earn 1.7% lower than national averages. However, Saint Louis currently ranks 497 statewide for Python Developer job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.
