As of July 01, 2026, the average salary for an Advanced Practice Nurse in Mississippi is $102,941 per year, which breaks down to an hourly rate of $49.
However, an Advanced Practice Nurse's salary can vary significantly. Here’s a look at the typical salary range:
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Advanced Practice Nurse Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $109,505 | $9,125 | $2,106 | $53 |
| Average | $102,941 | $8,578 | $1,980 | $49 |
| 25th Percentile | $97,433 | $8,119 | $1,874 | $47 |
Moonlight Medical - Greenville, MS
Fast Pace Health - Forest, MS
Fast Pace Health - Vicksburg, MS
Fast Pace Health - Grenada, MS
An Advanced Practice Nurse's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of an Advanced Practice Nurse's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Advanced Practice Nurse | $100,234 |
| Intermediate Level Advanced Practice Nurse | $100,646 |
| Senior Level Advanced Practice Nurse | $102,652 |
| Specialist Level Advanced Practice Nurse | $105,355 |
| Expert Level Advanced Practice Nurse | $105,837 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Advanced Practice Nurses. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Advanced Practice Nurse roles, the industry you choose can impact your earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Edu., Gov't. & Nonprofit, offers compensation 20% above the average. Conversely, Advanced Practice Nurse positions in Healthcare typically offer lower base pay, as this sector often view Advanced Practice Nurse as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Edu., Gov't. & Nonprofit | $123,530 | $59.0 | 20% |
Understanding how an Advanced Practice Nurse's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $109,505 | $9,125 | $2,106 | $53 |
| Average | $102,941 | $8,578 | $1,980 | $49 |
| 25th Percentile | $97,433 | $8,119 | $1,874 | $47 |
Ready to take the next step in your career? Browse thousands of current Advanced Practice Nurse job openings on our job board. Use the search bar below to find your perfect match.
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