NGS Scientist Salary at Janssen Global Services Llc BETA

A leader in the pharmaceutical industry is seeking a Scientist to join their team. Reporting to the Associate Director of Analytical Development, the Scientist will be responsible for the development of biophysical and analytical chemistry methods to further gene therapy products throughout clinical development, as well as performing BLA-enabling characterization studies. In this role you are encouraged to interact and collaborate across other functions within the company. **H1B transfers not permitted** **Full time onsite - half in lab half in office** Responsibilities: The Scientist will: Investigate and evaluate cutting edge biophysical and analytical instrumentation for AAV, AAV-Ab characterization Develop methods to quantitatively measure the purity and heterogeneity of AAV gene therapy vectors, including empty capsid, aggregation, and capsid protein purity Evaluate and implement new analytical platforms, such as Mass Photometry, SEC-MALS, and HPLC, to characterize AAV particles P

About Ormoni Ormoni is an intelligent drug design company. Our aims are threefold: 1. generate training-scale polypeptide drug activity data; 2. train our foundation drug model, OPM, to design first-in-class and best-in-class therapies; 3. develop these therapies at an unprecedented pace to help patients in need. We integrate megascale sequence-activity data generation with gigascale evolutionary sequence-structure maps to train the Ormoni Polypeptide Model for comprehensive drug design. In doing so, Ormoni collapses the billion-dollar, decade-long drug development process into discrete, rapid computational cycles, enabling better therapies, with faster development, for more patients. The Role Ormoni is seeking a (Senior) Scientist – Biology to develop cell-based and in vivo assays for functional screening, hit identification, and lead optimization of therapeutic polypeptides. This individual will play a key role in establishing and advancing our biological research capabilities, colla

Portal is a start-up cell engineering platform company focused on enabling next generation cell engineering and cell analytics across research and clinical applications. We are implementing a simplified approach to intracellular delivery, focused on accelerating advances enabled by the new generation of RNA, gene editing, and AI-driven technologies. Our initial product suite is based on a proprietary mechanical delivery system capable of delivering many different types of cargo to a broad range of cell types. Our technology's ability to be used stand-alone or as an integrated component of third-party systems provides a significant opportunity to broadly impact the fields of biological research and cellular therapeutics. As we grow our team, we are seeking an innovative and motivated scientist with a molecular biology and cell engineering background to join our group in developing a library of molecules that would enable transient cell modifications complementary to editing technologies

Scientist / Senior Scientist - Immunology Company Overview GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s lab, a pioneer in synthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency and speed. GC Therapeutics is based in Cambridge, MA. For additional information, please visit www.gc-tx.com. Job Purpose GC Therapeutics is seeking a talented and highly motivated Scientist or Senior Scientist for our Discoveryteam. This role will apply immunology approaches to bring a new class of cellular therapies to patients using GCTx’s Human TFomeTM platform, a synthetic biology-driven technology to differentiate human stem cells. The candidate will have s

POSITION SUMMARY: This role will support our purpose of advancing the understanding of disease in order to enable precision diagnostics. As a Scientist I, this position will work with cross functional teams to bring innovative, multiplexed serology quality control materials to market to serve the diagnostics and blood screening community. This scientist will support timelines and priorities and be a contributor to team’s workflow as needed to meet internal and external customer needs. To perform this job successfully, an individual must be able to capably perform each of the following essential functions: Proactively communicates upward and cross-functionally with colleagues to build relationships throughout the organization to clearly articulated goals and priorities. Provide technical support for product development and manufacture of new serological products including IVD controls, reference materials, and QC panels. Provide support for investigations and trouble-shooting activities

About Codify Therapeutics Codify Therapeutics is an innovative startup committed to leveraging alternative splicing to discover transformational medicines. Our mission is to develop groundbreaking treatments that address unmet medical needs and improve the lives of patients. Leveraging cutting-edge technologies from world-renowned scientific founders, Codify is dedicated to pushing the boundaries of cancer research and treatment. Job Description As a Scientist at Codify Therapeutics, you will play a key role in our growing organization, both to meet R&D needs and to drive projects in the Platform and Target Discovery group. This position offers a unique opportunity to collaborate with cross-functional teams and be a part of the early scientific team building a new and exciting therapeutic modality. Responsibilities Design and perform cell-based models and develop assays for new therapeutic target discovery Techniques may include CRISPR and/or lentivirus based genetic manipulation, and

Job Title: Scientist, Preformulation 📍 Location: Cambridge, MA 📄 Contract Length: 6 months Job Summary: We are seeking an exceptional candidate to contribute to preformulation research in a small, fast-paced, and highly collaborative team. This contract position is within the Formulation Sciences group of Technical Operations, supporting pre-clinical development. The candidate will work full-time onsite and be responsible for executing laboratory activities related to the transition of novel small molecule compounds from Discovery into Development. The role directly supports pre-clinical and clinical programs. An ideal candidate will have a strong foundation in analytical techniques such as UPLC/HPLC (Empower proficiency) and an understanding of early drug development processes and experiments. Experience in preformulation development and physicochemical characterization is highly desirable but not required. Ideal Experience: 0-3 years in pharmaceutical sciences (preformulation, anal

Primary Responsibilities · Targets evaluation, target indications and competitive landscape assessment for RNA-based therapeutics, including siRNA, ASO and related disciplines · Perform preclinical candidate screening and optimization via combined in vitro and in vivo assays, working withina cross-disciplinary group, including discovery chemistry, CMC and other relevant functions · Determine mechanism of action of drug targets; design and execute proof-of-concept studies to validate targets together with internal and/or external partners · Lead projects from inception to development candidate nomination · Prepare key preclinical, clinical and regulatory documents, and patent application · Effectively manage multiple programs and deliver quality result within sensitive timelines · Comply with appropriate SOPs; if needed, train associates to meet requirements; present research findings to project teams, governance bodies, or external meetings · Effectively communicate across all organiza