Scientist Salary at Qualitymetric Inc BETA

Respons. for expl. bioanal. test method dev. & sample anal. to charact. & report the absorption, distribution, metabolism, excretion, drug-drug interactions, & immunogenicity of lead mol. Dev. & qualif. test methods w/ criteria from app. reg. guidance to supp. quantitation of ASO lead mol. via hybridization-ELISA from cells, biofluids, & tissues in expl. studies. Dev. assays & conduct anal. to supp. the pharmacokinetic charact. of oligo drug candidates in rodents & monkeys, incl. their absorption, distribution, metabolism, or elimination properties. Estab. in vitro assays to charact. the potential of an ASO to stimulate the innate immune resp. in humans & eval. for all lead mol. Perf. assays to determine the potential drug-drug interactions of ASOs by measuring e.g., the induction of cytochrome P450 gene expression for all drug candidates. Dev. test methods & anal. samples to charact. immunogenicity resp. in animal studies & transfer test methods for regulated anal. of human samples. M

Description •Design and prototype drug-device combination and associated delivery system products •Conduct hands-on laboratory testing to evaluate the performance of the prototypes for supporting formulation, device, and combination product development (i.e. mechanical testing / Instron, in vitro release study testing, pipetting, buffer media) •Collaboration with scientists and technicians to analyze and resolve technical challenges •Maintain laboratory notebook and prepare technical reports •Support preclinical activities through hands-on manufacture and characterization of investigational products •Leverage tools (MATLAB, RStudio, Python, etc.) to analyze data and validate data to ensure data quality and reliability. Additional Skills & Qualifications Education: •Bachelor's degree from an accredited College/University in a relevant technical field (chemical engineering, Biomedical engineering, computer science or related field); open to BS, MS or PhD. Experience and Skills: Required:

Research Scientist 6-month contract Onsite in Lexington, MA Overview: As a Research Scientist in the Nucleic Acid Delivery, Formulations & Bioanalysis overall department, you will join a multinational and diverse team of Reseach Associates, specialists/Scientists. The goal of the team is to develop preclinical formulations of conjugated oligonucleotides apply advanced analytical characterization techniques and translate these to preclinical and clinical studies through internal and external collaborations in an automated high throughput manner. Responsibilities: • Identifies gaps in technological capabilities provides recommendations to guide the research agenda • Manage multiple external collaborations for deliverables • Optimize long-term storage and stability conditions of RNAi conjugates and oligonucleotide formulations in general • Develop robust analytical methods and assays for QC and developability assessments • Communicate findings internally to team via presentations and writ

Job Description: The Research Scientist at the School of Public Health is responsible for the investigation of deficits within scientific knowledge. The Research Scientist will devise, formulate, and execute investigative protocols and disseminate their insights through the publishing of findings in authoritative publications and documents. They create and research and presentations; spearhead data collection, analysis, and interpretation; and function as co-lead for joint research undertakings. The Research Scientist works within the center of Center for Gerontology & Health Care Research with PIs Andrew Zullo, PharmD, PhD, Kaley Hayes, PharmD, PhD, and Nina Joyce, PhD, faculty in the Departments of Epidemiology and Health Services, Policy, and Practice at the Brown University School of Public Health. Individuals in the position will also work with a variety of collaborators at other institutions, including the Hebrew SeniorLife Hinda and Arthur Marcus Institute For Aging Research, th

Layer Health was founded in 2023 by leading machine learning researchers from MIT and Harvard Medical School. We are building an AI layer that can accurately and scalably synthesize information from medical records, with the mission to reduce friction everywhere in healthcare. Our LLM-powered platform is solving chart review once and for all, across use cases. For health systems, our first product dramatically accelerates clinical registry abstraction in areas ranging from surgery and cardiology, to oncology. Our long term vision is for our AI layer to safely transform patient care and minimize unnecessary heartbreak. Layer Health's diverse founding team brings expertise across machine learning, UI/UX, large language models, and medicine. We're seeking outstanding hires to join our team as early members. This is an opportunity to contribute to a high-impact, collaborative, mission-driven team, and help define the next stage of growth for Layer Health. Together, we will create the AI la

We are seeking a Data Scientist to drive innovation in time series forecasting and anomaly detection. This role will be part of a team working on cutting-edge machine learning models and cloud-based solutions to enhance predictive capabilities across the organization. Key Responsibilities: Develop and deploy advanced forecasting models to predict trends, identify anomalies, and optimize decision-making. Design and implement AI/ML algorithms, managing the full lifecycle from data preparation to production deployment. Leverage cloud technologies such as AWS, Snowflake, and Databricks to scale machine learning solutions efficiently. Mentor and guide team members, providing technical expertise and support to drive best practices in AI/ML development. Collaborate with cross-functional teams, including data engineers and business stakeholders, to align AI/ML initiatives with company goals.

The Senior Associate/Scientist I is responsible for developing, optimizing and troubleshooting different unit operations in the manufacturing of LNPs and other non-viral gene delivery methods. This Scientist is also responsible for understanding the process parameters on the Drug product physical parameters. Essential Duties and Responsibilities Develop, optimize, and troubleshoot particle generation mixing technologies. Assess new unit operations and investigate their suitability for the process. Optimize and troubleshoot TFF ultra and defiltration steps. Characterize nanoparticles using various techniques and assays. Support scientists in experiments design, execution and analysis. Support lab activity duties; organization & inventory. Interface with clients and data presentations. Write Batch Records. Qualifications - To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the kno

The Fountain Group is currently seeking a Research Scientist for a prominent client of ours. This position is located in Lexington, MA. Details for the position are as follows: Job Description: Serve as a subject matter expert (SME) for late-stage clinical formulations of siRNA or oligonucleotides for systematic delivery, including the execution of analytical method development for solubility, viscosity, degradation, and rheological assessment for complex oligonucleotides formulations. Qualifications: MS or PhD Lab experience in formulation of siRNA or oligonucleotides for systemic delivery Experience acting as formulation subject matter expert for nucleic acid CLINICAL formulations Experience with analytical method development for solubility, viscosity, degradation, and rheological assessment for complex oligonucleotides formulations Compensation: $40-52.84 depending on experience (MS = level I, PhD = level II)