Septerna Salary

As of April 2026, the average annual salary for employees at Septerna in the United States is $118,844. This translates to an approximate hourly wage of $57. Salaries at Septerna typically range from $104,693 to $134,218 annually, reflecting the diverse roles and experience levels within the company.
How accurate does the salary look to you?

Current Job Openings at Septerna

Ready for your next career move? Explore current job openings at Septerna. Use the search tool below to find available positions by title and location and apply directly to start your career.

Is Septerna’s Pay Competitive? Salary Benchmarking Analysis

How does Septerna's compensation stack up against the industry and its key competitors? Our salary benchmarking analysis provides a clear comparison. The chart below visualizes this comparison alongside select peer companies.
Competitor / Benchmark Avg. Salary Variance Primary Market Influence Factor & Explanation
Aether $117,325
-1.3%
Confirms Aether is a direct competitor vying for the exact same talent pool.
Bluestar Genomics Inc $100,280
-15.6%
Bluestar Genomics Inc operates with a leaner overhead structure, impacting base wage offers.
Actio Biosciences Inc $101,894
-14.3%
Normalized for lower cost-of-living zones where Actio Biosciences Inc primarily operates.
Proclara Biosciences Inc $105,564
-11.2%
Reflects market rates for standard general contracting, differing from specialized roles.
Biotechnology Industry $130,524
+9.8%
Pay variances are driven by organizational scale, specialized skill requirements, or geographic cost-of-living factors.
Need More Granular Data? The analysis above provides a high-level market overview. To benchmark specific job codes, adjust for real-time cost-of-living changes, or access verified HR-reported datasets, upgrade to Salary.com for Business. Precision matters when building your compensation strategy.

Employee Reviews: Working at Septerna

Considering a career at Septerna? Explore authentic employee reviews to learn about the work environment, career growth opportunities, pay transparency and benefits. These first-hand insights can help you set realistic compensation expectations and make informed career decisions.
Project ownership is encouraged, though accountability and feedback systems are underdeveloped. Working in this biotech company has been incredibly rewarding. Ideas are encouraged from everyone, and there's a shared passion for our scientific mission. Excellent internal communication and scientific infrastructure.
Schedules are predictable, and benefits are competitive. the scale of research is massive, yet individual contributions are valued. Training and career advancement paths are clear and accessible. Everyone contributes, and ideas are discussed openly and respectfully. Managers provide guidance but are less involved in day-to-day development. It’s a safe place to work, and it is inspiring. I feel emp...
The work is challenging in the best way, and the support system is excellent. It’s incredibly inspiring to see the direct impact our work can potentially have on patients' lives. Resources are accessible, and innovation is constantly encouraged.

Septerna Overview

Website
www.septerna.com
Founded In
2022
Employees
<25 employees
Industry
Biotechnology
Headquarter Address
250 E Grand Ave South San Francisco California CA 94080
Revenue
<$5 Million
Phone Number
+1 6503383533
Social Media
About Septerna
Septerna is a biotechnology company with a focus on small molecule medicines targeting G protein-coupled receptors (GPCRs) with headquarters in San Francisco, CA.

What Benefits Does Septerna Offer Beyond Salary?

A competitive compensation package is more than just a salary. Septerna offers a comprehensive benefits package designed to support your health, financial future, and overall well-being. Below are the most common key benefits:
Social Security
401(K)
Disability
Healthcare
Pension
Time Off (days)
Work at Septerna?
Share your experience
How Much Should You Be Earning?

Get an estimated calculation of how much you should be earning and insight into your career options.

illustration

What Is the Cost of Living Near San Francisco?

Understanding the cost of living near San Francisco is key to truly evaluating a salary offer or your current compensation at Septerna.
San Francisco's Cost of Living Index is approximately 243.5 (143.5% more expensive than US average; 74.2% more than CA average). One of the most expensive cities globally, extreme housing costs, high transportation, and very high prices for all goods/services. When planning your budget based on a salary from Septerna, consider these typical monthly expenses:
Expense Category Estimated Monthly Cost Key Considerations / Notes
Housing (1-BR Apt Rent) $3,200 - $5,000+ A significant portion of Septerna salary. Location choices impact this heavily.
Utilities (Basic) $200 - $320 Electricity, Heating, Cooling, Water etc.
Public Transportation $81 (Muni Monthly Pass 'M') Essential for most commuters; car ownership is costly.
Groceries (Single Person) $550 - $850 Can be higher with more dining out or specialty stores.
Personal & Leisure $600 - $1,200+ Dining out, entertainment, shopping. Highly variable.
Healthcare (Individual) $450 - $850+ Varies significantly by plan & employer contribution.
Subtotal (Excluding Taxes) $5,081 - $8,221+ This subtotal does not include income taxes (federal, state, local), which can significantly impact your take-home pay.

FAQs of Septerna

1. What is the typical salary range (low to high) for most roles at Septerna?

The typical annual salary range for most roles at Septerna is approximately from $104,693 to $134,218. It's important to remember that these are overall averages, actual salaries vary significantly based on specific job titles, years of experience, skills, and location.

2. How much does Septerna pay compared to Aether?

The average annual salary at Septerna is $118,844, or an hourly wage of $57, in comparison to Aether which pays $117,325 per year or $56 per hour.

3. Do salaries differ significantly between departments at Septerna?

Yes, salaries often differ between departments at Septerna due to varying market demand for specific skill sets and the nature of the roles. For example, technical roles in Engineering or IT may command different salary ranges compared to roles in Marketing or Human Resources.

4. How does experience level affect salary at Septerna?

Experience level is a significant factor in determining salary at Septerna, as it is with most employers. Generally, employees with more years of relevant experience and a proven track record can command higher salaries. For example, a senior-level role will typically have a higher pay band than an entry-level or mid-career position within the same job family.

5. How can I determine if a salary offer from Septerna in San Francisco is fair given the local cost of living?

To determine if a salary offer from Septerna in San Francisco is fair, first compare the gross salary to our data for similar roles at Septerna and its competitors (see our similar company salaries section) . Then, critically, use our "Cost of Living Insights for San Francisco" to understand its purchasing power.

6. What factors influence salary increases at Septerna?

Salary increases at Septerna are likely influenced by a combination of factors, including: individual employee performance against set goals, overall company performance and profitability, budget availability, changes in the market rate for similar roles (market adjustments), and sometimes cost-of-living increases.