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Clinical Research Assistant I Salary in the United States

How much does a Clinical Research Assistant I make in the United States?

As of September 01, 2026, the average salary for a Clinical Research Assistant I in the United States is $61,390 per year, which breaks down to an hourly rate of $30.

However, a Clinical Research Assistant I's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $79,157
  • Majority Range (25th-75th percentile): $52,790 to $70,690
  • Entry-Level (10th percentile): $44,960

Key Factors That Influence Clinical Research Assistant I Salaries

A Clinical Research Assistant I's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Clinical Research Assistant Salaries?

Experience is a primary driver of a Clinical Research Assistant I's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Research Nurse Leader (0-0 years): $94,789
  • Clinical Research Assistant I (0-2 years): $61,344
  • Clinical Trials Research Associate II (2-4 years): $70,978
  • Clinical Research Lead Scientist (4-7 years): $100,812
  • Clinical Research Programs Manager (7+ years): $108,894
Job Role Years of Experience Average Salary
Clinical Research Nurse Leader0-0 years$94,789
Clinical Research Assistant I0-2 years$61,344
Clinical Trials Research Associate II2-4 years$70,978
Clinical Research Lead Scientist4-7 years$100,812
Clinical Research Programs Manager7+ years$108,894

Top Paying Cities for Clinical Research Assistant Is

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $77,390
  • San Francisco: $76,590
  • Oakland: $74,990

What Skills Can Increase a Clinical Research Assistant I's Salary?

Demanded Skills for the Role:

  • Integrity (Mentioned in 5.09% Job Postings): Is about having strong principles and values, which you demonstrate through your conduct in the work environment. A common integrity definition states that people with integrity do the right thing even when nobody is watching.
  • Oncology (Mentioned in 2.46% Job Postings): Designing, constructing, and repairing dental prosthetics and restorative and orthodontic devices to help patients correct dental conditions.
  • Data Collection (Mentioned in 1.46% Job Postings): Data collection is the process of gathering and measuring information on targeted variables in an established system, which then enables one to answer relevant questions and evaluate outcomes. Data collection is a component of research in all fields of study including physical and social sciences, humanities, and business. While methods vary by discipline, the emphasis on ensuring accurate and honest collection remains the same. The goal for all data collection is to capture quality evidence that allows analysis to lead to the formulation of convincing and credible answers to the questions that have been posed.
Skills Demand Percentage
Integrity 5.09%
Oncology 2.46%
Data Collection 1.46%

What skills can make your compensation higher?

Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Clinical Research Assistant I's salary.

  • Line Management: Can increase your salary by up to 33%.
  • Dedication: Can increase your salary by up to 9%.
  • Patient Safety: Can increase your salary by up to 7%.
Skill Salary Salary % Increase
Line Management $81,649
33%
Dedication $66,915
9%
Patient Safety $65,687
7%

Clinical Research Assistant I Salary by Company Size: Startups vs. Enterprise

Clinical Research Assistant I salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $69,018. While startup companies pay approximate $58,601.

Clinical Research Assistant I Salary by Company Size

Company Size Employees Average Salary
Startup 1~50 $58,601
Growth Stage 51~500 $61,917
Established 501~5000 $66,701
Enterprise 5000+ $69,018

Clinical Research Assistant I Salary by Industry: Top Paying Sectors

For Clinical Research Assistant I roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Edu., Gov't. & Nonprofit sectors offer the strongest compensation, at 20% above the average. In contrast, Clinical Research Assistant positions in Pharmaceuticals or Biotechnology typically offer lower base pay, as these industries often view Clinical Research Assistant I as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Research Assistant I

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$73,668$35.020%
Edu., Gov't. & Nonprofit$67,529$32.010%

Clinical Research Assistant I Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Research Assistant I's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on September 01, 2026
$52,790
Average $61,390/year
$70,690
$4,399
Average $5,116/month
$5,891
$1,015
Average $1,181/week
$1,359
$25
Average $30/hour
$34
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $70,690 $5,891 $1,359 $34
Average $61,390 $5,116 $1,181 $30
25th Percentile $52,790 $4,399 $1,015 $25

Clinical Research Assistant I Salary Growth & Career Path

Promotions are the fastest way to increase your earnings. As a Clinical Research Assistant I, you have the following paths for advancement. The table below compares the salary raises for common next-step roles. By comparing these figures, you can choose the career path that best meets your financial goals.

Clinical Research Assistant I Salary Growth and Career Path
Next Step Role Estimate Salary Projected Raise
Clinical Data Monitor II $77,500 26%
Clinical Trials Research Associate II $71,000 16%

Most common benefits for Clinical Research Assistant I

  • Social Security
  • 401 (k)
  • Disability
  • Healthcare
  • Pension
  • Time Off (days)

Common company salaries for Clinical Research Assistant I

Here are companies hiring for Clinical Research Assistant I and their salaries, click below for more details.

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FAQ about Clinical Research Assistant I

1. What industry pays the highest salary for Clinical Research Assistant I?

The Healthcare industry offers the highest average compensation for Clinical Research Assistant I roles, with salaries approximately 20% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

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