Clinical Research Assistant II Salary in the United States
How much does a Clinical Research Assistant II make in the United States?
As of August 01, 2026, the average salary for a Clinical Research Assistant II in the United States is $70,990 per year, which breaks down to an hourly rate of $34.
However, a Clinical Research Assistant II's salary can vary significantly. Here’s a look at the typical salary range:
Top Earners (90th percentile): $84,745
Majority Range (25th-75th percentile): $63,590 to $78,190
Key Factors That Influence Clinical Research Assistant II Salaries
A Clinical Research Assistant II's salary isn't a fixed number.
It's shaped by several important factors.
Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.
How Experience Level Affects Clinical Research Assistant Salaries?
Experience is a primary driver of a Clinical Research Assistant II's salary.
As you build your skills and take on more complex tasks, your compensation generally increases.
Here's how the average salary grows at different career stages:
Clinical Research Nurse Leader (0-0 years): $94,795
Clinical Trials Research Associate I (0-2 years): $61,342
Clinical Research Assistant II (2-4 years): $70,981
Clinical Research Lead Scientist (4-7 years): $100,805
Clinical Research Programs Manager (7+ years): $108,897
Job Role
Years of Experience
Average Salary
Clinical Research Nurse Leader
0-0 years
$94,795
Clinical Trials Research Associate I
0-2 years
$61,342
Clinical Research Assistant II
2-4 years
$70,981
Clinical Research Lead Scientist
4-7 years
$100,805
Clinical Research Programs Manager
7+ years
$108,897
$94,795Clinical ...
$61,342Clinical ...
$70,981Clinical ...
$100,805Clinical ...
$108,897Clinical ...
View as Table
View as Graph
What Am I Worth?
How Do Clinical Research Assistant II Salaries Vary from State to State?
Your salary can change significantly depending on where you work.
States with a higher cost of living and strong industrial sectors
often pay more to attract Clinical Research Assistant IIs.
For example, consider the average annual salaries in these key locations:
Top Paying Cities for Clinical Research Assistant IIs
Salaries can also vary between different cities.
Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay.
Here are a few examples of average annual salaries in different U.S. cities:
San Jose: $89,590
San Francisco: $88,590
Oakland: $86,690
San Jose, CA$89,590
San Francisco, CA$88,590
Oakland, CA$86,690
New York, NY$81,790
Paramus, NJ$80,790
Queens Village, NY$80,790
Passaic, NJ$80,690
Bergenfield, NJ$80,690
Huntington, NY$80,490
Stamford, CT$80,490
Newark, NJ$79,990
Bridgeport, CT$79,790
Vallejo, CA$79,690
New Brunswick, NJ$79,690
Petaluma, CA$79,590
Middlesex, NJ$79,490
Santa Cruz, CA$79,390
Somerset, NJ$79,390
Boston, MA$78,890
Monterey, CA$78,690
Seattle, WA$78,490
Santa Rosa, CA$78,490
Los Angeles, CA$78,490
Juneau, AK$78,290
Washington, DC$78,190
Orange, CA$77,990
Santa Ana, CA$77,790
Anaheim, CA$77,690
Anchorage, AK$77,690
Long Beach, CA$77,690
Santa Maria, CA$77,390
Everett, WA$77,390
Danbury, CT$77,190
Bremerton, WA$77,090
Tacoma, WA$76,790
New Suffolk, NY$76,790
Sacramento, CA$76,790
Santa Barbara, CA$76,690
Brockton, MA$76,590
San Diego, CA$76,590
Trenton, NJ$76,590
Fairbanks, AK$76,390
Lompoc, CA$76,190
Lowell, MA$76,190
Ventura, CA$76,090
Nashua, NH$76,090
Stockton, CA$76,090
Modesto, CA$75,590
Poughkeepsie, NY$75,390
Kennewick, WA$75,290
Olympia, WA$75,290
New Haven, CT$75,290
Lawrence, MA$74,990
Hartford, CT$74,990
New Bedford, MA$74,890
Richland, WA$74,890
Riverside, CA$74,890
Bakersfield, CA$74,790
Portsmouth, NH$74,690
Norwich, CT$74,690
New London, CT$74,690
San Bernardino, CA$74,690
New Britain, CT$74,690
Atlantic City, NJ$74,690
Boulder, CO$74,490
Portland, OR$74,390
Worcester, MA$74,390
Minneapolis, MN$74,190
Philadelphia, PA$74,090
Honolulu, HI$73,890
Saint Paul, MN$73,790
Vineland, NJ$73,790
Providence, RI$73,590
Chicago, IL$73,390
Springfield, MA$73,290
Bellingham, WA$73,290
Baltimore, MD$73,190
Chico, CA$73,090
Pittsfield, MA$72,890
Manchester, NH$72,690
Spokane, WA$72,390
Denver, CO$72,390
Albany, NY$72,090
Troy, NY$72,090
Nassau, NY$71,990
Schenectady, NY$71,890
Wilmington, DE$71,790
Burlington, VT$71,690
Salem, OR$71,690
Portland, ME$71,490
Yakima, WA$71,390
Rochester, MN$71,190
Reno, NV$71,190
Fresno, CA$71,190
Milwaukee, WI$71,090
Allentown, PA$70,990
Ann Arbor, MI$70,990
Detroit, MI$70,990
Colorado Springs, CO$70,890
Syracuse, NY$70,890
Carson City, NV$70,890
Houston, TX$70,790
Eugene, OR$70,690
Gary, IN$70,590
Springfield, OR$70,590
Bismarck, ND$70,590
Galveston, TX$70,490
Medford, OR$70,390
Fort Collins, CO$70,390
Concord, NH$70,290
Austin, TX$70,290
Mesa, AZ$70,190
Reading, PA$70,190
Phoenix, AZ$70,190
Dallas, TX$70,090
Saint Cloud, MN$70,090
Madison, WI$69,990
Utica, NY$69,790
Rochester, NY$69,690
Des Moines, IA$69,690
Raleigh, NC$69,690
Atlanta, GA$69,590
Battle Creek, MI$69,490
Salt Lake City, UT$69,490
Lancaster, PA$69,390
Harrisburg, PA$69,290
Kansas City, MO$69,190
Kansas City, KS$69,190
Champaign, IL$69,190
Fort Worth, TX$69,190
Columbus, OH$69,190
Boca Raton, FL$69,190
Pittsburgh, PA$69,190
Indianapolis, IN$69,090
Cleveland, OH$69,090
Richmond, VA$69,090
Las Vegas, NV$68,990
Cincinnati, OH$68,990
Petersburg, VA$68,890
Huntsville, AL$68,790
Lansing, MI$68,790
Lebanon, PA$68,790
Buffalo, NY$68,690
Charlotte, NC$68,690
Racine, WI$68,690
Appleton, WI$68,690
Pueblo, CO$68,690
Dayton, OH$68,690
Gastonia, NC$68,590
Saint Louis, MO$68,590
York, PA$68,590
Elkhart, IN$68,590
Billings, MT$68,590
Binghamton, NY$68,490
Toledo, OH$68,490
Rock Hill, SC$68,490
Lorain, OH$68,490
Beaumont, TX$68,490
Benton Harbor, MI$68,490
Rockford, IL$68,390
Springfield, IL$68,390
Elyria, OH$68,390
Fargo, ND$68,390
Flagstaff, AZ$68,290
Fort Lauderdale, FL$68,290
Duluth, MN$68,190
Miami, FL$68,190
Grand Forks, ND$68,190
Cheyenne, WY$68,190
Bangor, ME$67,990
Cedar Rapids, IA$67,990
Hialeah, FL$67,890
Grand Rapids, MI$67,890
Durham, NC$67,890
Louisville, KY$67,890
Casper, WY$67,790
Scranton, PA$67,690
New Orleans, LA$67,690
Virginia Beach, VA$67,690
Akron, OH$67,690
Sarasota, FL$67,590
Peoria, IL$67,590
Charleston, SC$67,490
Baton Rouge, LA$67,490
Nashville, TN$67,490
Omaha, NE$67,490
Green Bay, WI$67,490
Jamestown, NY$67,390
Davenport, IA$67,390
Tucson, AZ$67,390
Port Arthur, TX$67,290
Evansville, IN$67,290
Bradenton, FL$67,290
Saint Petersburg, FL$67,290
Tampa, FL$67,290
Santa Fe, NM$67,090
Orlando, FL$66,990
Clearwater, FL$66,990
Newport News, VA$66,790
Albuquerque, NM$66,790
High Point, NC$66,790
La Crosse, WI$66,790
Canton, OH$66,790
Corpus Christi, TX$66,690
Ogden, UT$66,690
Salisbury, NC$66,590
Norfolk, VA$66,590
Laramie, WY$66,590
Rock Island, IL$66,590
Saginaw, MI$66,590
Jacksonville, FL$66,590
Memphis, TN$66,490
Fort Myers, FL$66,490
Boise, ID$66,490
Moline, IL$66,490
Tulsa, OK$66,390
Waterloo, IA$66,390
Spartanburg, SC$66,290
Lincoln, NE$66,290
Fort Wayne, IN$66,290
Provo, UT$66,290
Cedar Falls, IA$66,190
South Bend, IN$66,090
Greensboro, NC$66,090
San Antonio, TX$66,090
Savannah, GA$65,990
Muskegon, MI$65,990
Birmingham, AL$65,990
Winston Salem, NC$65,990
Lake Charles, LA$65,790
Anderson, IN$65,790
Lexington, KY$65,790
Wichita, KS$65,690
Lima, OH$65,690
Tuscaloosa, AL$65,690
Augusta, GA$65,690
Greenville, SC$65,690
Columbia, SC$65,590
Springfield, OH$65,590
Asheville, NC$65,490
Bloomington, IN$65,390
Knoxville, TN$65,190
Shreveport, LA$65,190
Roanoke, VA$65,090
Wilmington, NC$65,090
Topeka, KS$64,890
Frankfort, KY$64,890
Oklahoma City, OK$64,890
Chillicothe, OH$64,890
Longview, TX$64,890
Melbourne, FL$64,790
Terre Haute, IN$64,690
Sioux Falls, SD$64,690
Mobile, AL$64,690
Altoona, PA$64,690
Killeen, TX$64,590
Amarillo, TX$64,590
Fayetteville, AR$64,490
Chattanooga, TN$64,490
Sioux City, IA$64,390
Idaho Falls, ID$64,390
Lynchburg, VA$64,390
Gainesville, FL$64,290
Youngstown, OH$64,190
Clarksville, TN$64,190
Daytona Beach, FL$64,190
Lafayette, LA$64,190
Little Rock, AR$64,190
Portsmouth, OH$64,190
Pensacola, FL$64,090
Temple, TX$64,090
Hopkinsville, KY$63,890
Erie, PA$63,890
Florence, SC$63,890
Charleston, WV$63,790
Great Falls, MT$63,690
Helena, MT$63,590
Waco, TX$63,590
Macon, GA$63,590
Tallahassee, FL$63,590
Fayetteville, NC$63,590
Pine Bluff, AR$63,490
Vincennes, IN$63,390
Lubbock, TX$63,390
Alamogordo, NM$63,390
Twin Falls, ID$63,290
Rapid City, SD$63,290
Greenville, MS$63,190
Jackson, MS$63,190
Huntington, WV$63,190
Parkersburg, WV$63,090
Montgomery, AL$63,090
Wichita Falls, TX$62,990
Springfield, MO$62,990
Biloxi, MS$62,990
Monroe, LA$62,890
Sumter, SC$62,790
Columbus, GA$62,790
Johnstown, PA$62,790
Pascagoula, MS$62,690
Abilene, TX$62,690
Kingsport, TN$62,490
Albany, GA$62,490
Gulfport, MS$62,490
Alexandria, LA$62,190
Fort Smith, AR$62,090
El Paso, TX$61,890
Las Cruces, NM$61,490
Harlingen, TX$61,390
Pocatello, ID$61,290
Florence, AL$61,290
Brownsville, TX$61,190
Mcallen, TX$61,090
Dothan, AL$60,990
Columbus, MS$60,590
Altus, OK$60,190
Lawton, OK$60,090
Pierre, SD$59,890
What Skills Can Increase a Clinical Research Assistant II's Salary?
Demanded Skills for the Role:
Integrity (Mentioned in 5.06% Job Postings): Is about having strong principles and values, which you demonstrate through your conduct in the work environment. A common integrity definition states that people with integrity do the right thing even when nobody is watching.
Clinical Monitoring (Mentioned in 4.58% Job Postings): Clinical Monitoring refers to the observation of a disease, condition or one or several medical parameters over time.
Career Development (Mentioned in 2.19% Job Postings): Refers to the process an individual may undergo to evolve their occupational status. It is the process of making decisions for long term learning, to align personal needs of physical or psychological fulfillment with career advancement opportunities.
See More Skills
Skills
Demand Percentage
Integrity
5.06%
Clinical Monitoring
4.58%
Career Development
2.19%
What skills can make your compensation higher?
Mastering certain specialized skills can lead to a significant increase in pay.
Here are examples of skills and the potential impact they can have on a Clinical Research Assistant II's salary.
Drug Development: Can increase your salary by up to 12%.
Insight: Can increase your salary by up to 10%.
Clinical Operations: Can increase your salary by up to 7%.
Skill
Salary
Salary % Increase
Drug Development
$79,509
12%
Insight
$78,089
10%
Clinical Operations
$75,959
7%
Innovation
$75,249
6%
Collaboration
$74,540
5%
Sense Of Urgency
$74,540
5%
Get Latest Data
Clinical Research Assistant II Salary by Company Size: Startups vs. Enterprise
Clinical Research Assistant II salary potential scales significantly with company size.
Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $79,880.
While startup companies pay approximate $67,847.
Clinical Research Assistant II Salary by Company Size
Company Size
Employees
Average Salary
Startup
1~50
$67,847
Growth Stage
51~500
$71,680
Established
501~5000
$77,208
Enterprise
5000+
$79,880
Clinical Research Assistant II Salary by Industry: Top Paying Sectors
For Clinical Research Assistant II roles, the industry you choose can affect earning potential
by as much as 40% (the gap between the highest and lowest paying industries).
Data shows that the Healthcare and Pharmaceuticals
sectors offer the strongest compensation, at 20% above the average.
In contrast, Clinical Research Assistant positions in Edu., Gov't. & Nonprofit or Biotechnology typically offer lower base pay,
as these industries often view Clinical Research Assistant II as a support function rather than a direct revenue driver.
The top paying industries for a Clinical Research Assistant II
Industry Sector
Average Annual Salary
Average Hourly Rate
Pay vs.Avg
Healthcare
$85,188
$41.0
20%
Pharmaceuticals
$78,089
$38.0
10%
Clinical Research Assistant II Salary: Hourly Rate, Weekly Pay, and Monthly Pay
Understanding how a Clinical Research Assistant II's annual salary breaks down can help with budgeting.
Below, you can see the average hourly rate, weekly pay, and monthly pay for this role.
Use the buttons to switch between different pay periods.
Hourly
Monthly
Weekly
Yearly
Table View
Last Updated on August 01, 2026
$63,590
Average$70,990/year
$78,190
$5,299
Average$5,916/month
$6,516
$1,223
Average$1,365/week
$1,504
$31
Average$34/hour
$38
Annual Salary
Monthly Pay
Weekly Pay
Hourly Wage
75th Percentile
$78,190
$6,516
$1,504
$38
Average
$70,990
$5,916
$1,365
$34
25th Percentile
$63,590
$5,299
$1,223
$31
Clinical Research Assistant II Salary Growth & Career Path
Promotions are the fastest way to increase your earnings.
As a Clinical Research Assistant II, you have the following paths for advancement.
The table below compares the salary raises for common next-step roles.
By comparing these figures, you can choose the career path that best meets your financial goals.
Clinical Research Assistant II Salary Growth and Career Path
Next Step Role
Estimate Salary
Projected Raise
Clinical Data Monitor III
$92,400
30%
Clinical Research Lead Scientist
$100,900
42%
Salaries of jobs related to Clinical Research Assistant II
Salaries for a Clinical Research Assistant II can change over time,
reflecting shifts in market demand and the overall economy.
The median salary decreased from $67,580 in 2023
to around $67,466 in 2025,
reflecting changes in demand, location, experience, and the wider economy.
For a detailed analysis of Clinical Research Assistant II salary trends,
.
Average Annual Salary of Clinical Research Assistant II Over Time
2022
$???
2023
$67,580
2024
$67,693
2025
$67,466
2026
$???
2027
$???
Year
Average Annual Salary
2022
View More
2023
$67,580
2024
$67,693
2025
$67,466
2026
View More
2027
View More
Most common benefits for Clinical Research Assistant II
Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
For Employers
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Compensation Planning
Common company salaries for Clinical Research Assistant II
Here are companies hiring for Clinical Research Assistant II and their salaries, click below for more details.
C
$128,509/per year
C R Bard Inc
Biotechnology
the United States
H
$124,697/per year
Henry Schein Canada
Biotechnology
the United States
N
$123,899/per year
Nordex Inc
Biotechnology
the United States
N
$120,416/per year
Nipro Corp
Biotechnology
the United States
E
$115,870/per year
Enovis
Biotechnology
the United States
A
$114,553/per year
Advanced Research Projects Agency - Energy
Biotechnology
the United States
M
$112,110/per year
MiniMed Inc
Biotechnology
the United States
L
$111,500/per year
Labcorp Drug Development
Biotechnology
the United States
L
$110,229/per year
Life Technologies Corp
Biotechnology
the United States
Z
$106,224/per year
Zimmer Biomet
Biotechnology
the United States
P
$103,077/per year
Promontory Therapeutics
Biotechnology
the United States
S
$102,181/per year
Steris PLC
Biotechnology
the United States
G
$97,274/per year
Gavin Conferences Pty Ltd
Biotechnology
the United States
E
$94,764/per year
Endeavor BioMedicines
Biotechnology
the United States
R
$94,402/per year
Replay Holdings LLC
Biotechnology
the United States
P
$94,235/per year
Pleno Inc
Biotechnology
the United States
S
$93,666/per year
Simulaids Inc
Biotechnology
the United States
N
$88,880/per year
NOIRLab/CAS
Biotechnology
the United States
O
$86,468/per year
Onward Technology
Biotechnology
the United States
L
$84,895/per year
LED Medical Diagnostics Inc
Biotechnology
the United States
E
$84,682/per year
Eyeco Ltd
Biotechnology
the United States
P
$84,523/per year
Paerosol
Biotechnology
the United States
I
$83,525/per year
IONIQ Sciences Inc
Biotechnology
the United States
S
$82,815/per year
Stateside PPE
Biotechnology
the United States
D
$82,041/per year
Digi Bio
Biotechnology
the United States
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FAQ about Clinical Research Assistant II
1. What industry pays the highest salary for Clinical Research Assistant II?
The Healthcare industry offers the highest average compensation for Clinical Research Assistant II roles,
with salaries approximately 20% above the market median.
Where Does Our Salary Data Come From?
Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.
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