As of June 01, 2026, the average salary for a Nurse Practitioner in South Carolina is $109,405 per year, which breaks down to an hourly rate of $53.
However, a Nurse Practitioner's salary can vary significantly. Here’s a look at the typical salary range:
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Nurse Practitioner Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $116,313 | $9,693 | $2,237 | $56 |
| Average | $109,405 | $9,117 | $2,104 | $53 |
| 25th Percentile | $103,532 | $8,628 | $1,991 | $50 |
MultiCare Health System - Olympia, SC
Self Regional Healthcare - Physician - Greenwood, SC
Self Regional Healthcare - Physician - Greenwood, SC
McLeod Health - Florence, SC
A Nurse Practitioner's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.
Experience is a primary driver of a Nurse Practitioner's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Nurse Practitioner | $107,038 |
| Intermediate Level Nurse Practitioner | $107,477 |
| Senior Level Nurse Practitioner | $109,611 |
| Specialist Level Nurse Practitioner | $112,498 |
| Expert Level Nurse Practitioner | $113,013 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Nurse Practitioners. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
Nurse Practitioner salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $116,197. While startup companies pay approximate $98,967.
| Company Size | Employees | Average Salary |
|---|---|---|
| Startup | 1~50 | $98,967 |
| Growth Stage | 51~500 | $104,484 |
| Established | 501~5000 | $112,403 |
| Enterprise | 5000+ | $116,197 |
Understanding how a Nurse Practitioner's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $116,313 | $9,693 | $2,237 | $56 |
| Average | $109,405 | $9,117 | $2,104 | $53 |
| 25th Percentile | $103,532 | $8,628 | $1,991 | $50 |
Ready to take the next step in your career? Browse thousands of current Nurse Practitioner job openings on our job board. Use the search bar below to find your perfect match.
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