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As of August 01, 2026, the average salary for an Advanced Nurse Practitioner in Missouri is $108,765 per year, which breaks down to an hourly rate of $52.
However, an Advanced Nurse Practitioner's salary can vary significantly. Here’s a look at the typical salary range:
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Advanced Nurse Practitioner Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $115,702 | $9,642 | $2,225 | $56 |
| Average | $108,765 | $9,064 | $2,092 | $52 |
| 25th Percentile | $102,946 | $8,579 | $1,980 | $49 |
CareSTL Health - Saint Louis, MO
The Nurse Practitioner Group LLC - Branson, MO
Advanced Family Medicine and Wellness Center - Joplin, MO
GoHealth Urgent Care - Saint Louis, MO
An Advanced Nurse Practitioner's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of an Advanced Nurse Practitioner's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Advanced Nurse Practitioner | $105,905 |
| Intermediate Level Advanced Nurse Practitioner | $106,340 |
| Senior Level Advanced Nurse Practitioner | $108,459 |
| Specialist Level Advanced Nurse Practitioner | $111,315 |
| Expert Level Advanced Nurse Practitioner | $111,825 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Advanced Nurse Practitioners. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Advanced Nurse Practitioner roles, the industry you choose can impact your earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Edu., Gov't. & Nonprofit, offers compensation 20% above the average. Conversely, Advanced Nurse Practitioner positions in Healthcare typically offer lower base pay, as this sector often view Advanced Nurse Practitioner as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Edu., Gov't. & Nonprofit | $130,518 | $63.0 | 20% |
Understanding how an Advanced Nurse Practitioner's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $115,702 | $9,642 | $2,225 | $56 |
| Average | $108,765 | $9,064 | $2,092 | $52 |
| 25th Percentile | $102,946 | $8,579 | $1,980 | $49 |
Ready to take the next step in your career? Browse thousands of current Advanced Nurse Practitioner job openings on our job board. Use the search bar below to find your perfect match.
SSM Health
Saint Louis, MO
SSM Health | Saint Louis, MO
SSM Health is an Equal Opportunity Employer:Community Description:About SSM Health:Variety, Flexibility, and Purpose. Find your next Primary Care role at S... more
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Truhealth
Rolla, MO
Truhealth | Rolla, MO
Ready to Make a Difference in Healthcare. At TruHealth, we're transforming care for seniors in long-term care with an innovative, proactive model that prom... more
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Oak St. Health
Ballwin, MO
Oak St. Health | Ballwin, MO
Full Time Regional ProviderWe're building a world of health around every individual shaping a more connected, convenient and compassionate health experienc... more
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Medlead Careers
Saint Louis, MO
Medlead Careers | Saint Louis, MO
Job Description. Job Description. Are you a Nurse Practitioner with a passion for caring for the geriatric population. If so, this is an excellent opportun... more
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i4 Search Group Healthcare
Springfield, MO
i4 Search Group Healthcare | Springfield, MO
Job Description. Job Description. Nurse Practitioner. POSITION TYPE: Advanced Practice Professional. SPECIALTY UNIT. Registered Nurse Practitioner (NP). LO... more
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PALM Health
Saint Louis, MO
PALM Health | Saint Louis, MO
Job Description. Job Description. Description. Why PALM Health. PALM Health is an integrative medicine and wellness center offering a comprehensive range o... more
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