Senior Director, Clinical Operations Salary in North Carolina

How much does a Senior Director, Clinical Operations make in North Carolina?

As of August 01, 2026, the average salary for a Senior Director, Clinical Operations in North Carolina is $109,937 per year, which breaks down to an hourly rate of $53.

However, a Senior Director, Clinical Operations's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $125,994
  • Majority Range (25th-75th percentile): $98,476 to $118,342
  • Entry-Level (10th percentile): $88,041
Compensation Planning
Develop a Job Description
Pay Equity
2026 Compensation Trend
AI Onboarding
AI-Powered Talent
View as table View as graph 25% $98,476 10% $88,041 90% $125,994 75% $118,342 $109,937 50%(Median) Didn’t find job title? Click

Senior Director, Clinical Operations Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $118,342 $9,862 $2,276 $57
Average $109,937 $9,161 $2,114 $53
25th Percentile $98,476 $8,206 $1,894 $47
Check out Senior Director, Clinical Operations Job Openings in North Carolina
Director of Clinical Operations

North Carolina Retina Associates - Raleigh, NC

Associate Director of Clinical Operations

Grifols Shared Services North America, Inc - Durham, NC

Sr. Director, Technical Operations

MedPharm - Durham, NC

Senior Director, Servicing Operations

Mission Lane - Charlotte, NC

Search More Senior Director, Clinical Operations Jobs in North Carolina

Key Factors That Influence Senior Director, Clinical Operations Salaries

A Senior Director, Clinical Operations's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Senior Director, Clinical Operations Salaries?

Experience is a primary driver of a Senior Director, Clinical Operations's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $102,031
  • Early Career (1-2 years): $103,098
  • Mid-Level (2-4 years): $104,876
  • Senior-Level (5-8 years): $106,653
  • Expert (over 8 years): $109,567
Levels Salary
Entry Level Senior Director, Clinical Operations$102,031
Intermediate Level Senior Director, Clinical Operations$103,098
Senior Level Senior Director, Clinical Operations$104,876
Specialist Level Senior Director, Clinical Operations$106,653
Expert Level Senior Director, Clinical Operations$109,567
$102,031 0 yr
$103,098 < 2 yrs
$104,876 2-4 yrs
$106,653 5-8 yrs
$109,567 > 8 yrs
View as Table
View as Graph

What Am I Worth?

Top Paying Cities for Senior Director, Clinical Operations

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • Morven: $104,889
  • Mount Holly: $111,267
  • Mount Mourne: $109,690

Senior Director, Clinical Operations Salary by Industry: Top Paying Sectors

For Senior Director, Clinical Operations roles, the industry you choose can impact your earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Healthcare, offers compensation 20% above the average. Conversely, Senior Director, Clinical Operations positions in Edu., Gov't. & Nonprofit typically offer lower base pay, as this sector often view Senior Director, Clinical Operations as a support function rather than a direct revenue driver.

The top paying industry for a Senior Director, Clinical Operations

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$131,925$63.020%

Senior Director, Clinical Operations Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Senior Director, Clinical Operations's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on August 01, 2026

Find Your Next Senior Director, Clinical Operations Job

Ready to take the next step in your career? Browse thousands of current Senior Director, Clinical Operations job openings on our job board. Use the search bar below to find your perfect match.

United States
  • Openwork

    Lincolnton, NC

    Openwork | Lincolnton, NC

    Job Description. Job Description. Senior Director, Quality Operations. Support quality initiatives and ensure compliance with cGMPs are maintained at the f... more

    5 Days Ago

  • ProKidney

    Winston Salem, NC

    ProKidney | Winston Salem, NC

    Position SummaryThe Senior Director, Quality Operations is responsible for providing strategic and operational leadership across all aspects of GMP Quality... more

    6 Days Ago

  • Implaion Recruiting

    Butner, NC

    Implaion Recruiting | Butner, NC

    Senior Director, Clinical Development REMOTECritical ElementsIndividual contributor / strong leader who wants to be very hands onProven expertise in global... more

    6 Days Ago

  • Brightspeed

    Charlotte, NC

    Brightspeed | Charlotte, NC

    Job Description. Job Description. Company Description. At Brightspeed, we are reimagining how people live, work, play and connect by providing fast, reliab... more

    6 Days Ago

  • Confidential

    Charlotte, NC

    Confidential | Charlotte, NC

    Senior Medical Director, Clinical Development (Medical Monitoring). About the Company. Rapidly growing organization in the oncology & hematology industry. ... more

    6 Days Ago

  • Bethany Medical

    High Point, NC

    Bethany Medical | High Point, NC

    PETERS MEDICAL RESEARCHPartnering with patients today for tomorrow's miracles. Established Clinical Research Company is seeking a Senior Clinical Research ... more

    6 Days Ago

For Employees

Get a Salary Increase

Analyze the market and your qualifications to negotiate your salary with confidence.

Search Job Openings

Search thousands of open positions to find your next opportunity.

For Employers

Adjust Employee Salary

Individualize employee pay based on unique job requirements and personal qualifications.

Price My Industry Jobs

Get the latest market price for benchmark jobs and jobs in your industry.

Cost of Living In North Carolina

Cost of Living in North Carolina is
-5.0% Lower
than the National Average

Use Salary.com's Cost of Living Calculator to find out what income you need to maintain your standard of living in a different city and how much more or less money you need to budget for basic expenses.

Explore Cost of Living Calculator
Empower Your Team

Salary.com experts will help you thrive your workplaces.

Find Salary.com Comp Consulting
See Salary Trends in 2025

Salary.com provides salary survey data for thousands of industry Jobs.

Price Your Company Jobs and Make Pay Fair

Where Does Our Salary Data Come From?

Salary.com salary estimates, histograms, trends, and comparisons are derived from both employer job postings and third-party data sources. We also provide multiple percentiles of salary information for your reference, click here to know Why the Salary Midpoint Formula Is Crucial to Getting Pay Equity Right. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target.

Are you an HR manager or compensation specialist?

Salary.com's CompAnalyst platform offers:

  • Detailed skills and competency reports for specific positions
  • Job and employee pricing reports
  • Compensation data tools, salary structures, surveys and benchmarks.
Learn about CompAnalyst