Manager Of Clinical Operations Salary in the United States

How much does a Manager Of Clinical Operations make in the United States?

As of August 01, 2026, the average salary for a Manager Of Clinical Operations in the United States is $71,449 per year, which breaks down to an hourly rate of $34.

However, a Manager Of Clinical Operations's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $85,392
  • Majority Range (25th-75th percentile): $61,792 to $78,747
  • Entry-Level (10th percentile): $52,999
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View as table View as graph 25% $61,792 10% $52,999 90% $85,392 75% $78,747 $71,449 50%(Median) Didn’t find job title? Click

Manager Of Clinical Operations Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $78,747 $6,562 $1,514 $38
Average $71,449 $5,954 $1,374 $34
25th Percentile $61,792 $5,149 $1,188 $30
Check out Manager Of Clinical Operations Job Openings in the United States
Vice President Clinical Operations

Confidential - Columbus, OH

Vice President of Clinical Operations

Confidential - Columbus, OH

Clinical Manager

Fresenius Medical Care - Columbus, OH

Operations Manager

Savage Transload Network LLC - Columbus, OH

Search More Manager Of Clinical Operations Jobs in the United States

Key Factors That Influence Manager Of Clinical Operations Salaries

A Manager Of Clinical Operations's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

Top Paying Cities for Manager Of Clinical Operations

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $90,118
  • San Francisco: $89,131
  • Oakland: $87,253

What Skills Can Increase a Manager Of Clinical Operations's Salary?

Demanded Skills for the Role:

  • Leadership (Mentioned in 10.17% Job Postings): Knowledge of and ability to employ effective strategies that motivate and guide other members within our business to achieve optimum results.
  • Clinical Operations (Mentioned in 2.17% Job Postings): Clinical Operations refer to the activities that support the clinical trial process from start-up to close out. Ensures there is proper planning, appropriate conduct through the process, safety of patients and use of quality data.
  • Continuous Quality Improvement (Mentioned in 1.61% Job Postings): Continuous Quality Improvement (CQI) is a deliberate, defined process which is focused on activities that are responsive to community needs and improving population health.
See More Skills
Skills Demand Percentage
Leadership 10.17%
Clinical Operations 2.17%
Continuous Quality Improvement 1.61%
What skills can make your compensation higher?
Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Manager Of Clinical Operations's salary.
  • Clinical Trial: Can increase your salary by up to 8%.
  • Clinical Research: Can increase your salary by up to 6%.
  • Commitment: Can increase your salary by up to 5%.
Skill Salary Salary % Increase
Clinical Trial
$77,164
8%
Clinical Research
$75,736
6%
Commitment
$75,021
5%
Accountability
$74,307
4%
Confidentiality
$74,307
4%
Project Management
$73,592
3%
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Manager Of Clinical Operations Salary by Industry: Top Paying Sectors

For Manager Of Clinical Operations roles, the industry you choose can impact your earning potential by as much as 20% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Healthcare, offers compensation 10% above the average. Conversely, Manager Of Clinical Operations positions in Edu., Government & Nonprofit typically offer lower base pay, as this sector often view Manager Of Clinical Operations as a support function rather than a direct revenue driver.

The top paying industry for a Manager Of Clinical Operations

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$78,593$38.010%

How Education impacts a Manager Of Clinical Operations's Salary?

Your level of education can impact your salary potential. While many Manager Of Clinical Operations enter the field with a High School Diploma or Technical Certificate degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Manager Of Clinical Operations with a High School Diploma or Technical Certificate is between $74,771 and $81,097).

Manager Of Clinical Operations Salaries by Degree Level

Typical Education for Manager Of Clinical Operations
Degree Level % of user with this level of education
No Diploma 0.8%
High School 26.2%
Associates 15.3%
Bachelors 34.4%
Masters 20.9%
Doctorate 2.4%
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Manager Of Clinical Operations Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Manager Of Clinical Operations's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on August 01, 2026

Salary Trends for Manager Of Clinical Operations

Salaries for a Manager Of Clinical Operations can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $74,361 in 2023 to around $73,341 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Manager Of Clinical Operations salary trends, .

Average Annual Salary of Manager Of Clinical Operations Over Time

2022
$???
2023
$74,361
2024
$74,410
2025
$73,341
2026
$???
2027
$???
Year Average Annual Salary
2022
View More
2023 $74,361
2024 $74,410
2025 $73,341
2026
View More
2027
View More

Most common benefits for Manager Of Clinical Operations

Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
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Common company salaries for Manager Of Clinical Operations

Here are companies hiring for Manager Of Clinical Operations and their salaries, click below for more details.

Find Your Next Manager Of Clinical Operations Job

Ready to take the next step in your career? Browse thousands of current Manager Of Clinical Operations job openings on our job board. Use the search bar below to find your perfect match.

United States
  • Jushi

    Columbus, OH

    Jushi | Columbus, OH

    Job Description. Job Description. Want to make a meaningful difference in peoples’ lives while earning a competitive salary. At Jushi Holdings Inc. ”) (CSE... more

    3 Days Ago

  • Ulta Beauty

    Columbus, OH

    Ulta Beauty | Columbus, OH

    Ulta Beauty - - Responsibilities: Lead a team of Task Associates and the Merchandise Manager. Drive top-line sales growth and manage payroll budgets. Revie... more

    3 Days Ago

  • Reco Equipment Inc

    Columbus, OH

    Reco Equipment Inc | Columbus, OH

    Job Description. Job Description. Description. RECO Equipment Inc. is a full-line distributor supplying heavy and compact equipment — new, used, and rental... more

    4 Days Ago

  • Community Kitchen Inc.

    Columbus, OH

    Community Kitchen Inc. | Columbus, OH

    Job Description. Job Description. Interested applicants may submit a resume to: ceo. @CommunityKitchenColumbus.org. . This is a full-time, exempt position ... more

    5 Days Ago

  • Ohiohealth

    Columbus, OH

    Ohiohealth | Columbus, OH

    We are more than a health system.We are a belief system.We believe wellness and sickness are both part of a lifelong partnership, and that everyone could u... more

    1 Day Ago

  • Luminary Hospice

    Columbus, OH

    Luminary Hospice | Columbus, OH

    Job Description. Job Description. Job Title/Position. Clinical Service Manager. Reports To: Director of Clinical Services. About Luminary Hospice. At Lumin... more

    1 Day Ago

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FAQ about Manager Of Clinical Operations

1. What industry pays the highest salary for Manager Of Clinical Operations?

The Healthcare industry offers the highest average compensation for Manager Of Clinical Operations roles, with salaries approximately 10% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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