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As of August 01, 2026, the average salary for a Medical Nurse in Missouri is $80,995 per year, which breaks down to an hourly rate of $39.
However, a Medical Nurse's salary can vary significantly. Here’s a look at the typical salary range:
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Medical Nurse Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $87,915 | $7,326 | $1,691 | $42 |
| Average | $80,995 | $6,750 | $1,558 | $39 |
| 25th Percentile | $75,218 | $6,268 | $1,446 | $36 |
BJC HealthCare - Manchester, MO
BJC HealthCare - Manchester, MO
BJC HealthCare - Farmington, MO
AMN Healthcare - Lees Summit, MO
A Medical Nurse's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Medical Nurses. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Medical Nurse roles, the industry you choose can affect earning potential by as much as 35% (the gap between the highest and lowest paying industries). Data shows that the Software & Networking and Biotechnology sectors offer the strongest compensation, at 15% above the average. In contrast, Medical Nurse positions in Edu., Gov't. & Nonprofit or MFG Nondurable typically offer lower base pay, as these industries often view Medical Nurse as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Software & Networking | $93,144 | $45.0 | 15% |
| Biotechnology | $91,119 | $44.0 | 12% |
| Energy & Utilities | $87,070 | $42.0 | 7% |
| Insurance | $85,045 | $41.0 | 5% |
Understanding how a Medical Nurse's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $87,915 | $7,326 | $1,691 | $42 |
| Average | $80,995 | $6,750 | $1,558 | $39 |
| 25th Percentile | $75,218 | $6,268 | $1,446 | $36 |
Ready to take the next step in your career? Browse thousands of current Medical Nurse job openings on our job board. Use the search bar below to find your perfect match.
TactStaff
Kansas City, MO
TactStaff | Kansas City, MO
Registered Nurse - Medical Surgical. Seeking experienced Registered Nurses to provide comprehensive medical-surgical care in a high-volume hospital setting... more
4 Days Ago
AHS Staffing
Saint Louis, MO
AHS Staffing | Saint Louis, MO
Registered Nurse - Med - Surg - Travel | St. Louis, Missouri. Estimated Weekly Pay. $1915.08. Start Date. 08/31/2026 |. Duration. 13 Weeks. Shift. 3 x 12hr... more
4 Days Ago
Saint Luke's Hospital of Kansas City
Chillicothe, MO
Saint Luke's Hospital of Kansas City | Chillicothe, MO
Saint Luke’s Hospital of Kansas City is seeking a Registered Nurse for our Medical-Surgical unit. In this role, you will deliver compassionate, evidence-ba... more
4 Days Ago
Saint Luke's Hospital of Kansas City
Lees Summit, MO
Saint Luke's Hospital of Kansas City | Lees Summit, MO
Saint Luke’s Hospital of Kansas City is seeking a Registered Nurse for our Medical Telemetry unit. In this role, you’ll provide evidence-based care to adul... more
4 Days Ago
AMN Healthcare
Saint Louis, MO
AMN Healthcare | Saint Louis, MO
Job Title. EMR-EPIC Scrub Color - Black Mercy Hospital South earned A grade in The Leapfrog Group's Fall 2024 Hospital Safety Grade. Mercy Hospital South h... more
5 Days Ago
SkyBridge Resources
Poplar Bluff, MO
SkyBridge Resources | Poplar Bluff, MO
Travel Registered Nurse - Medical-Surgical. SkyBridge Healthcare is currently seeking a registered nurse with medical-surgical experience for a 13-week con... more
5 Days Ago
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