As of October 01, 2026, the average annual salary for Medical Surgical Nurse in the US is $103,515, equivalent to $50 per hour, $1,991 weekly, or $8,626 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Medical Surgical Nurse in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for Medical Surgical Nurse in the US vary widely, spanning from $86,424 to $126,401. Most professionals fall between the 25th percentile ($94,569) and 75th percentile ($115,494), while top earners (90th percentile) make $126,401 per year. This $20,925 pay gap underscores opportunities for salary growth through certifications, specialized skills like Planning or Nursing Practice, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, District of Columbia Medical Surgical Nurse often earn 10.7% above national averages due to demand from Fortune 8 companies and industry startups. Professionals are advised to focus on high-growth sectors like Edu., Gov't. & Nonprofit to offset market challenges.
