Medical Nurse Salary in South Dakota

How much does a Medical Nurse make in South Dakota?

As of August 01, 2026, the average salary for a Medical Nurse in South Dakota is $77,474 per year, which breaks down to an hourly rate of $37.

However, a Medical Nurse's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $90,119
  • Majority Range (25th-75th percentile): $71,948 to $84,093
  • Entry-Level (10th percentile): $66,916
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View as table View as graph 25% $71,948 10% $66,916 90% $90,119 75% $84,093 $77,474 50%(Median) Didn’t find job title? Click

Medical Nurse Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $84,093 $7,008 $1,617 $40
Average $77,474 $6,456 $1,490 $37
25th Percentile $71,948 $5,996 $1,384 $35
Check out Medical Nurse Job Openings in South Dakota
Medical Surgical Nurse

AMN Healthcare - Sioux Falls, SD

Registered Nurse or Medical Assistant

Avera Health - Sioux Falls, SD

Registered Nurse or Medical Assistant

Avera Health - Sioux Falls, SD

Registered Nurse or Medical Assistant

Avera Health - Yankton, SD

Search More Medical Nurse Jobs in South Dakota

Key Factors That Influence Medical Nurse Salaries

A Medical Nurse's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

Top Paying Cities for Medical Nurses

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • Alcester: $78,282
  • Aurora: $78,698
  • Baltic: $77,851

Medical Nurse Salary by Industry: Top Paying Sectors

For Medical Nurse roles, the industry you choose can affect earning potential by as much as 35% (the gap between the highest and lowest paying industries). Data shows that the Software & Networking and Biotechnology sectors offer the strongest compensation, at 15% above the average. In contrast, Medical Nurse positions in Edu., Gov't. & Nonprofit or MFG Nondurable typically offer lower base pay, as these industries often view Medical Nurse as a support function rather than a direct revenue driver.

The top paying industries for a Medical Nurse

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Software & Networking$89,095$43.015%
Biotechnology$87,159$42.012%
Energy & Utilities$83,285$40.07%
Insurance$81,348$39.05%

Medical Nurse Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Medical Nurse's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on August 01, 2026

Find Your Next Medical Nurse Job

Ready to take the next step in your career? Browse thousands of current Medical Nurse job openings on our job board. Use the search bar below to find your perfect match.

United States
  • Sanford Health

    Rapid City, SD

    Sanford Health | Rapid City, SD

    Sanford Health - 1730 Haines Avenue - Responsibilities: Ensures the health, comfort and safety of patients. Documents a thorough medical history from patie... more

    2 Days Ago

  • Sanford Health

    Rapid City, SD

    Sanford Health | Rapid City, SD

    Sanford Health - 7236 Jordan Drive - Responsibilities: Ensure the health, comfort and safety of patients. Document thorough medical history from patient. C... more

    2 Days Ago

  • Turnwell Mental Health

    Yankton, SD

    Turnwell Mental Health | Yankton, SD

    MWI, an entity of Turnwell Mental Health Network, is committed to maintaining a company for mental health that is a vital step in defining culture, guiding... more

    2 Days Ago

  • Avera Health

    Sioux Falls, SD

    Avera Health | Sioux Falls, SD

    Job Title. Avera Orthopedics 69th & Louise. Worker Type: Regular. Work Shift: Day Shift (United States of America). Pay Range: $20.00 - $41.25. Position Hi... more

    4 Days Ago

  • Worldwide Medical Staffing

    Eagle Butte, SD

    Worldwide Medical Staffing | Eagle Butte, SD

    Job Description. Job Description. Worldwide Medical Staffing is a Native-Veteran-owned staffing agency with a 30-year service history with US Government Ho... more

    2 Days Ago

  • Monument Health

    Spearfish, SD

    Monument Health | Spearfish, SD

    Monument Health - - Responsibilities: Assist nursing staff in providing patient personal care, bathing, and hygiene. Assist with admission, dismissal, and ... more

    3 Days Ago

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Cost of Living In South Dakota

Cost of Living in South Dakota is
-9.1% Lower
than the National Average

Use Salary.com's Cost of Living Calculator to find out what income you need to maintain your standard of living in a different city and how much more or less money you need to budget for basic expenses.

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