Know your market value with insights across roles — from individual contributors to executive pay and overall company compensation trends.
Access a suite of powerful calculators to make data-driven career decisions.
Automate pay cycles, manage job architectures, and ensure pay equity with AI-powered compensation platforms.
Access validated salary benchmarks, labor market trends, and minimum wage data to stay competitive.
Participate in and purchase industry-specific salary surveys to obtain the most accurate, peer-reported pay data.
As of August 01, 2026, the average salary for a Principal Clinical Research Associate in Maine is $58,044 per year, which breaks down to an hourly rate of $28.
However, a Principal Clinical Research Associate's salary can vary significantly. Here’s a look at the typical salary range:
Compensation Planning
Develop a Job Description
Pay Equity
2026 Compensation Trend
Smart Recruiting
Recruit with AI
Principal Clinical Research Associate Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $66,331 | $5,528 | $1,276 | $32 |
| Average | $58,044 | $4,837 | $1,116 | $28 |
| 25th Percentile | $49,164 | $4,097 | $945 | $24 |
Confidential - BIRMINGHAM, AL
Confidential - NASHVILLE, TN
Confidential - HOUSTON, TX
Confidential - CHICAGO, IL
A Principal Clinical Research Associate's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Principal Clinical Research Associate's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Staff Nur... Level Principal Clinical Research Associate | $90,651 |
| Principal... Level Principal Clinical Research Associate | $58,660 |
| Clinical ... Level Principal Clinical Research Associate | $67,878 |
| Scientist... Level Principal Clinical Research Associate | $96,398 |
| Clinical ... Level Principal Clinical Research Associate | $104,136 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Principal Clinical Research Associates. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Principal Clinical Research Associate roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Edu., Gov't. & Nonprofit sectors offer the strongest compensation, at 20% above the average. In contrast, Principal Clinical Research Associate positions in Pharmaceuticals or Biotechnology typically offer lower base pay, as these industries often view Principal Clinical Research Associate as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Healthcare | $69,652 | $33.0 | 20% |
| Edu., Gov't. & Nonprofit | $63,848 | $31.0 | 10% |
Understanding how a Principal Clinical Research Associate's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $66,331 | $5,528 | $1,276 | $32 |
| Average | $58,044 | $4,837 | $1,116 | $28 |
| 25th Percentile | $49,164 | $4,097 | $945 | $24 |
Ready to take the next step in your career? Browse thousands of current Principal Clinical Research Associate job openings on our job board. Use the search bar below to find your perfect match.
Confidential
NEW YORK, NY
Confidential | NEW YORK, NY
Associate Vice President, Research Lead. About the Company. A financial services firm seeking a research leader for executive intelligence and relationship... more
1 Month Ago
Confidential
CHICAGO, IL
Confidential | CHICAGO, IL
Associate General Counsel, Research & Innovation. About the Company. Well-ranked pediatric healthcare provider. Industry. Hospital & Health Care. Type. Non... more
1 Month Ago
Confidential
NEWARK, DE
Confidential | NEWARK, DE
Associate Vice President, Research Administration & Sponsored Programs. About the Company. Prominent research-intensive university. Industry. Higher Educat... more
26 Days Ago
Confidential
KNOXVILLE, TN
Confidential | KNOXVILLE, TN
Associate Vice President for Institutional Research & Analysis. About the Company. Tennessee's land-grant university system serving students and advancing ... more
1 Month Ago
Confidential
MINNEAPOLIS, MN
Confidential | MINNEAPOLIS, MN
Senior Associate Vice President for Research Development & Strategy. About the Company. Top-tier higher education institution. Industry. Higher Education. ... more
1 Month Ago
Confidential
PITTSBURGH, PA
Confidential | PITTSBURGH, PA
Associate Vice President for Research Computing & Data. About the Company. Thriving private research university. Industry. Higher Education. Type. Educatio... more
1 Month Ago
Get a Salary Increase
Analyze the market and your qualifications to negotiate your salary with confidence.
Search Job Openings
Search thousands of open positions to find your next opportunity.
Adjust Employee Salary
Individualize employee pay based on unique job requirements and personal qualifications.
Price My Industry Jobs
Get the latest market price for benchmark jobs and jobs in your industry.
Use Salary.com's Cost of Living Calculator to find out what income you need to maintain your standard of living in a different city and how much more or less money you need to budget for basic expenses.
Explore Cost of Living CalculatorSalary.com experts will help you thrive your workplaces.
Salary.com provides salary survey data for thousands of industry Jobs.
Salary.com salary estimates, histograms, trends, and comparisons are derived from both employer job postings and third-party data sources. We also provide multiple percentiles of salary information for your reference, click here to know Why the Salary Midpoint Formula Is Crucial to Getting Pay Equity Right. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target.
Salary.com's CompAnalyst platform offers:
