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As of August 01, 2026, the average salary for a Principal Clinical Research Associate in Tennessee is $55,632 per year, which breaks down to an hourly rate of $27.
However, a Principal Clinical Research Associate's salary can vary significantly. Here’s a look at the typical salary range:
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Principal Clinical Research Associate Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $63,575 | $5,298 | $1,223 | $31 |
| Average | $55,632 | $4,636 | $1,070 | $27 |
| 25th Percentile | $47,121 | $3,927 | $906 | $23 |
Castle Biosciences Inc - Nashville, TN
Nature Careers - Memphis, TN
Medpace - Nashville, TN
Medpace - Nashville, TN
A Principal Clinical Research Associate's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Principal Clinical Research Associate's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Staff Nur... Level Principal Clinical Research Associate | $86,885 |
| Principal... Level Principal Clinical Research Associate | $56,223 |
| Clinical ... Level Principal Clinical Research Associate | $65,058 |
| Scientist... Level Principal Clinical Research Associate | $92,394 |
| Clinical ... Level Principal Clinical Research Associate | $99,810 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Principal Clinical Research Associates. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Principal Clinical Research Associate roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Edu., Gov't. & Nonprofit sectors offer the strongest compensation, at 20% above the average. In contrast, Principal Clinical Research Associate positions in Pharmaceuticals or Biotechnology typically offer lower base pay, as these industries often view Principal Clinical Research Associate as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Healthcare | $66,759 | $32.0 | 20% |
| Edu., Gov't. & Nonprofit | $61,196 | $29.0 | 10% |
Understanding how a Principal Clinical Research Associate's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $63,575 | $5,298 | $1,223 | $31 |
| Average | $55,632 | $4,636 | $1,070 | $27 |
| 25th Percentile | $47,121 | $3,927 | $906 | $23 |
Ready to take the next step in your career? Browse thousands of current Principal Clinical Research Associate job openings on our job board. Use the search bar below to find your perfect match.
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CHICAGO, IL
Confidential | CHICAGO, IL
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Associate Vice President, Research Lead. About the Company. A financial services firm seeking a research leader for executive intelligence and relationship... more
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CHICAGO, IL
Confidential | CHICAGO, IL
Associate General Counsel, Research & Innovation. About the Company. Well-ranked pediatric healthcare provider. Industry. Hospital & Health Care. Type. Non... more
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