As of January 01, 2026, the average annual salary for Senior Clinical Research Associate in the US is $79,439, equivalent to $38 per hour, $1,528 weekly, or $6,620 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Senior Clinical Research Associate in cities like Santa Clara, San Jose, and Fremont.
Annually Salaries for Senior Clinical Research Associate in the US vary widely, spanning from $63,604 to $94,700. Most professionals fall between the 25th percentile ($71,150) and 75th percentile ($87,427), while top earners (90th percentile) make $94,700 per year. This $16,277 pay gap underscores opportunities for salary growth through certifications, specialized skills like Integrity or Clinical Monitoring, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, District of Columbia Senior Clinical Research Associate often earn 10.7% above national averages due to demand from Fortune 44 companies and industry startups. Professionals are advised to focus on high-growth sectors like to offset market challenges.
