As of October 01, 2026, the average annual salary for general surgery nurse practitioner in Mississippi is $111,761, equivalent to $54 per hour, $2,149 weekly, or $9,313 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for general surgery nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for general surgery nurse practitioner in Mississippi vary widely, spanning from $100,270 to $125,236. Most professionals fall between the 25th percentile ($105,747) and 75th percentile ($118,815), while top earners (90th percentile) make $125,236 per year. This $13,068 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, Mississippi general surgery nurse practitioner often earn 10.8% lower than national averages due to demand from Fortune 65 companies. However, Mississippi currently ranks 51 nationwide for general surgery nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.
