As of October 01, 2026, the average annual salary for general surgery nurse practitioner in North Carolina is $119,093, equivalent to $57 per hour, $2,290 weekly, or $9,924 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for general surgery nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for general surgery nurse practitioner in North Carolina vary widely, spanning from $106,848 to $133,452. Most professionals fall between the 25th percentile ($112,683) and 75th percentile ($126,609), while top earners (90th percentile) make $133,452 per year. This $13,926 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, North Carolina general surgery nurse practitioner often earn 5.0% lower than national averages due to demand from Fortune 65 companies. However, North Carolina currently ranks 36 nationwide for general surgery nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
general surgery nurse practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile general surgery nurse practitioner Salary $106,848 NC October 01, 2026
25th Percentile general surgery nurse practitioner Salary $112,683 NC October 01, 2026
50th Percentile general surgery nurse practitioner Salary $119,093 NC October 01, 2026
75th Percentile general surgery nurse practitioner Salary $126,609 NC October 01, 2026
90th Percentile general surgery nurse practitioner Salary $133,452 NC October 01, 2026
25% $112,683 10% $106,848 90% $133,452 75% $126,609 $119,093 50%(Median) Didn’t find job title? Click
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What is A general surgery nurse practitioner ?

A general surgery nurse practitioner (NP) specializes in providing comprehensive care to surgical patients. Responsibilities include conducting pre-operative assessments, assisting in surgical procedures, managing post-operative care, and educating patients about recovery processes. NPs in this field collaborate with surgeons and other healthcare professionals to ensure optimal patient outcomes. The salary for a general surgery nurse practitioner varies based on factors such as geographic location, years of experience, and the type of healthcare facility. On average, salaries range from $90,...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Aberdeen, NC Avg. Salary $131,622 Date Updated October 01, 2026
Location Advance, NC Avg. Salary $134,373 Date Updated October 01, 2026
Location Ahoskie, NC Avg. Salary $131,786 Date Updated October 01, 2026
Location Alamance, NC Avg. Salary $134,733 Date Updated October 01, 2026
Location Albemarle, NC Avg. Salary $134,485 Date Updated October 01, 2026
Location Albertson, NC Avg. Salary $130,803 Date Updated October 01, 2026
Location Alexander, NC Avg. Salary $133,534 Date Updated October 01, 2026
Location Alexis, NC Avg. Salary $138,728 Date Updated October 01, 2026
Location Alliance, NC Avg. Salary $130,416 Date Updated October 01, 2026
Location Almond, NC Avg. Salary $131,336 Date Updated October 01, 2026
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