As of October 01, 2026, the average annual salary for general surgery nurse practitioner in South Carolina is $117,426, equivalent to $56 per hour, $2,258 weekly, or $9,786 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for general surgery nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for general surgery nurse practitioner in South Carolina vary widely, spanning from $105,353 to $131,584. Most professionals fall between the 25th percentile ($111,106) and 75th percentile ($124,837), while top earners (90th percentile) make $131,584 per year. This $13,731 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, South Carolina general surgery nurse practitioner often earn 6.3% lower than national averages due to demand from Fortune 65 companies. However, South Carolina currently ranks 42 nationwide for general surgery nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.
