As of August 01, 2026, the average annual salary for Internal Medicine Nurse in Colorado is $97,778, equivalent to $47 per hour, $1,880 weekly, or $8,148 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Internal Medicine Nurse in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Internal Medicine Nurse in Colorado vary widely, spanning from $85,439 to $115,059. Most professionals fall between the 25th percentile ($91,320) and 75th percentile ($106,823), while top earners (90th percentile) make $115,059 per year. This $15,503 pay gap underscores opportunities for salary growth through certifications, specialized skills like Planning or Nursing Process, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, Colorado Internal Medicine Nurse often earn 2.0% higher than national averages due to demand from Fortune 56 companies. However, Colorado currently ranks 13 nationwide for Internal Medicine Nurse job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Internal Medicine Nurse Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Internal Medicine Nurse Salary $85,439 CO August 01, 2026
25th Percentile Internal Medicine Nurse Salary $91,320 CO August 01, 2026
50th Percentile Internal Medicine Nurse Salary $97,778 CO August 01, 2026
75th Percentile Internal Medicine Nurse Salary $106,823 CO August 01, 2026
90th Percentile Internal Medicine Nurse Salary $115,059 CO August 01, 2026
25% $91,320 10% $85,439 90% $115,059 75% $106,823 $97,778 50%(Median) Didn’t find job title? Click
Change Search Criteria
Check out Internal Medicine Nurse jobs in Colorado

Internal Medicine Nurse Practitioner

Aya Locums - Colorado Springs, CO

Search More Internal Medicine Nurse Jobs in Colorado

What is An Internal Medicine Nurse ?

The salary for an Internal Medicine Nurse varies based on factors such as experience, location, and the healthcare facility. On average, these professionals earn between $70,000 and $100,000 annually. Entry-level positions may start around $60,000, while those with advanced certifications or extensive experience can exceed $100,000. Geographic location plays a significant role, with urban areas typically offering higher salaries due to the cost of living. Additionally, specialized skills and certifications can enhance earning potential. Benefits such as health insurance, retirement plans, and ...

Source: (as of 06/04/2025). Read more from

See user submitted job responsibilities for Internal Medicine Nurse.

Select a city to view specific salary and bonus information for Internal Medicine Nurse

Loading results...
Location Avg. Salary Date Updated
Location Jefferson, CO Avg. Salary $105,596 Date Updated August 01, 2026
Location Agate, CO Avg. Salary $103,420 Date Updated August 01, 2026
Location Aguilar, CO Avg. Salary $102,895 Date Updated August 01, 2026
Location Akron, CO Avg. Salary $103,261 Date Updated August 01, 2026
Location Alamosa, CO Avg. Salary $104,138 Date Updated August 01, 2026
Location Allenspark, CO Avg. Salary $107,910 Date Updated August 01, 2026
Location Alma, CO Avg. Salary $106,607 Date Updated August 01, 2026
Location Almont, CO Avg. Salary $107,193 Date Updated August 01, 2026
Location Amherst, CO Avg. Salary $102,930 Date Updated August 01, 2026
Location Anton, CO Avg. Salary $102,845 Date Updated August 01, 2026
Job Openings for Internal Medicine Nurse in Colorado

Jobs with a similar salary range to Internal Medicine Nurse : Rn, First Responder, Rn Resident