As of August 01, 2026, the average annual salary for Internal Medicine Nurse in North Carolina is $91,070, equivalent to $44 per hour, $1,751 weekly, or $7,589 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Internal Medicine Nurse in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Internal Medicine Nurse in North Carolina vary widely, spanning from $79,578 to $107,165. Most professionals fall between the 25th percentile ($85,054) and 75th percentile ($99,494), while top earners (90th percentile) make $107,165 per year. This $14,440 pay gap underscores opportunities for salary growth through certifications, specialized skills like Planning or Nursing Process, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, North Carolina Internal Medicine Nurse often earn 5.0% lower than national averages due to demand from Fortune 56 companies. However, North Carolina currently ranks 36 nationwide for Internal Medicine Nurse job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Internal Medicine Nurse Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Internal Medicine Nurse Salary $79,578 NC August 01, 2026
25th Percentile Internal Medicine Nurse Salary $85,054 NC August 01, 2026
50th Percentile Internal Medicine Nurse Salary $91,070 NC August 01, 2026
75th Percentile Internal Medicine Nurse Salary $99,494 NC August 01, 2026
90th Percentile Internal Medicine Nurse Salary $107,165 NC August 01, 2026
25% $85,054 10% $79,578 90% $107,165 75% $99,494 $91,070 50%(Median) Didn’t find job title? Click
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Internal Medicine Nurse Practitioner

Theoria Medical - Gastonia, NC

Internal Medicine Nurse Practitioner

Olympus Health - Lexington, NC

Internal Medicine Nurse Practitioner

CHS Recruiting - Greensboro, NC

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What is An Internal Medicine Nurse ?

The salary for an Internal Medicine Nurse varies based on factors such as experience, location, and the healthcare facility. On average, these professionals earn between $70,000 and $100,000 annually. Entry-level positions may start around $60,000, while those with advanced certifications or extensive experience can exceed $100,000. Geographic location plays a significant role, with urban areas typically offering higher salaries due to the cost of living. Additionally, specialized skills and certifications can enhance earning potential. Benefits such as health insurance, retirement plans, and ...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Aberdeen, NC Avg. Salary $95,325 Date Updated August 01, 2026
Location Advance, NC Avg. Salary $97,318 Date Updated August 01, 2026
Location Ahoskie, NC Avg. Salary $95,444 Date Updated August 01, 2026
Location Alamance, NC Avg. Salary $97,578 Date Updated August 01, 2026
Location Albemarle, NC Avg. Salary $97,399 Date Updated August 01, 2026
Location Albertson, NC Avg. Salary $94,732 Date Updated August 01, 2026
Location Alexander, NC Avg. Salary $96,710 Date Updated August 01, 2026
Location Alexis, NC Avg. Salary $100,472 Date Updated August 01, 2026
Location Alliance, NC Avg. Salary $94,452 Date Updated August 01, 2026
Location Almond, NC Avg. Salary $95,118 Date Updated August 01, 2026
Job Openings for Internal Medicine Nurse in North Carolina

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