As of August 01, 2026, the average annual salary for Medical Office Staff in South Carolina is $82,052, equivalent to $39 per hour, $1,578 weekly, or $6,838 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Medical Office Staff in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Medical Office Staff in South Carolina vary widely, spanning from $68,777 to $101,578. Most professionals fall between the 25th percentile ($75,104) and 75th percentile ($92,273), while top earners (90th percentile) make $101,578 per year. This $17,169 pay gap underscores opportunities for salary growth through certifications, specialized skills like Customer Service or Front Office, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, South Carolina Medical Office Staff often earn 6.3% lower than national averages due to demand from Fortune 60 companies. However, South Carolina currently ranks 42 nationwide for Medical Office Staff job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Medical Office Staff Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Medical Office Staff Salary $68,777 SC August 01, 2026
25th Percentile Medical Office Staff Salary $75,104 SC August 01, 2026
50th Percentile Medical Office Staff Salary $82,052 SC August 01, 2026
75th Percentile Medical Office Staff Salary $92,273 SC August 01, 2026
90th Percentile Medical Office Staff Salary $101,578 SC August 01, 2026
25% $75,104 10% $68,777 90% $101,578 75% $92,273 $82,052 50%(Median) Didn’t find job title? Click
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Check out Medical Office Staff jobs in South Carolina

CPA Office Support Staff

Wealth Training Academy, LLC - Greenville, SC

Temporary Office Staff Pool

Charleston County School District - Charleston, SC

Staff Nurse 5T, Medical, Full Time, Day Shift

Greenwood County Hospital Board - Greenwood, SC

Staff Nurse 5T, Medical, Full Time, Day Shift

Self Regional Healthcare - Greenwood, SC

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Medical Office Staff

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Location Avg. Salary Date Updated
Location Goose Creek, SC Avg. Salary $87,569 Date Updated August 01, 2026
Location Abbeville, SC Avg. Salary $84,155 Date Updated August 01, 2026
Location Adams Run, SC Avg. Salary $86,444 Date Updated August 01, 2026
Location Aiken, SC Avg. Salary $85,074 Date Updated August 01, 2026
Location Alcolu, SC Avg. Salary $81,793 Date Updated August 01, 2026
Location Allendale, SC Avg. Salary $83,568 Date Updated August 01, 2026
Location Anderson, SC Avg. Salary $84,960 Date Updated August 01, 2026
Location Andrews, SC Avg. Salary $83,305 Date Updated August 01, 2026
Location Arcadia, SC Avg. Salary $86,312 Date Updated August 01, 2026
Location Awendaw, SC Avg. Salary $87,009 Date Updated August 01, 2026
Job Openings for Medical Office Staff in South Carolina

Jobs with a similar salary range to Medical Office Staff : Office Lead, Regional Office Manager, Middle Office Manager