As of August 01, 2026, the average annual salary for Medical Surgical Nurse in Mississippi is $92,332, equivalent to $44 per hour, $1,776 weekly, or $7,694 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Medical Surgical Nurse in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for Medical Surgical Nurse in Mississippi vary widely, spanning from $77,093 to $112,785. Most professionals fall between the 25th percentile ($84,355) and 75th percentile ($103,038), while top earners (90th percentile) make $112,785 per year. This $18,683 pay gap underscores opportunities for salary growth through certifications, specialized skills like Planning or Nursing Practice, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, Mississippi Medical Surgical Nurse often earn 10.8% lower than national averages due to demand from Fortune 8 companies. However, Mississippi currently ranks 51 nationwide for Medical Surgical Nurse job salary. Professionals are advised to focus on high-growth sectors like Edu., Gov't. & Nonprofit to offset market challenges.
