As of August 01, 2026, the average annual salary for nurse informatics in Colorado is $112,063, equivalent to $54 per hour, $2,155 weekly, or $9,339 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for nurse informatics in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for nurse informatics in Colorado vary widely, spanning from $92,875 to $130,382. Most professionals fall between the 25th percentile ($102,019) and 75th percentile ($121,652), while top earners (90th percentile) make $130,382 per year. This $19,633 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Integrated Care, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, Colorado nurse informatics often earn 2.0% higher than national averages due to demand from Fortune 40 companies. However, Colorado currently ranks 13 nationwide for nurse informatics job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
nurse informatics Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile nurse informatics Salary $92,875 CO August 01, 2026
25th Percentile nurse informatics Salary $102,019 CO August 01, 2026
50th Percentile nurse informatics Salary $112,063 CO August 01, 2026
75th Percentile nurse informatics Salary $121,652 CO August 01, 2026
90th Percentile nurse informatics Salary $130,382 CO August 01, 2026
25% $102,019 10% $92,875 90% $130,382 75% $121,652 $112,063 50%(Median) Didn’t find job title? Click
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Check out nurse informatics jobs in Colorado

Nurse Practitioner

Woundara Wound Care - FORT WAYNE, IN

Nurse Practitioner

Desert Sage Health Centers - MOUNTAIN HOME, ID

REGISTERED NURSE

Siouxland Community Health Center - SIOUX CITY, IA

Registered Nurse

Richmond Healthcare & Rehab Center - RICHMOND, KS

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What is A nurse informatics ?

Nurse informatics professionals play a crucial role in integrating nursing science with information management and analytical sciences to enhance healthcare outcomes. They are responsible for managing and analyzing health information systems, ensuring data accuracy, and improving patient care through technology. Typical duties include collaborating with healthcare teams to implement electronic health records (EHR), training staff on new systems, and evaluating the effectiveness of informatics solutions. Salaries for nurse informatics specialists can vary widely based on factors such as educat...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Jefferson, CO Avg. Salary $107,364 Date Updated August 01, 2026
Location Agate, CO Avg. Salary $105,151 Date Updated August 01, 2026
Location Aguilar, CO Avg. Salary $104,617 Date Updated August 01, 2026
Location Akron, CO Avg. Salary $104,989 Date Updated August 01, 2026
Location Alamosa, CO Avg. Salary $105,881 Date Updated August 01, 2026
Location Allenspark, CO Avg. Salary $109,716 Date Updated August 01, 2026
Location Alma, CO Avg. Salary $108,391 Date Updated August 01, 2026
Location Almont, CO Avg. Salary $108,987 Date Updated August 01, 2026
Location Amherst, CO Avg. Salary $104,653 Date Updated August 01, 2026
Location Anton, CO Avg. Salary $104,566 Date Updated August 01, 2026
Job Openings for nurse informatics in Colorado

Jobs with a similar salary range to nurse informatics : Informaticist, Rn Clinical Data Abstractor, Informatics Analyst