As of August 01, 2026, the average annual salary for nurse informatics in Colorado is $112,063, equivalent to $54 per hour, $2,155 weekly, or $9,339 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for nurse informatics in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for nurse informatics in Colorado vary widely, spanning from $92,875 to $130,382. Most professionals fall between the 25th percentile ($102,019) and 75th percentile ($121,652), while top earners (90th percentile) make $130,382 per year. This $19,633 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or Integrated Care, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, Colorado nurse informatics often earn 2.0% higher than national averages due to demand from Fortune 40 companies. However, Colorado currently ranks 13 nationwide for nurse informatics job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.