As of September 01, 2026, the average annual salary for Orthopedic Surgery Nurse Practitioner in Colorado is $131,018, equivalent to $63 per hour, $2,520 weekly, or $10,918 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Orthopedic Surgery Nurse Practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Orthopedic Surgery Nurse Practitioner in Colorado vary widely, spanning from $117,547 to $146,814. Most professionals fall between the 25th percentile ($123,967) and 75th percentile ($139,286), while top earners (90th percentile) make $146,814 per year. This $15,319 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, Colorado Orthopedic Surgery Nurse Practitioner often earn 2.0% higher than national averages due to demand from Fortune 47 companies. However, Colorado currently ranks 13 nationwide for Orthopedic Surgery Nurse Practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Orthopedic Surgery Nurse Practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Orthopedic Surgery Nurse Practitioner Salary $117,547 CO September 01, 2026
25th Percentile Orthopedic Surgery Nurse Practitioner Salary $123,967 CO September 01, 2026
50th Percentile Orthopedic Surgery Nurse Practitioner Salary $131,018 CO September 01, 2026
75th Percentile Orthopedic Surgery Nurse Practitioner Salary $139,286 CO September 01, 2026
90th Percentile Orthopedic Surgery Nurse Practitioner Salary $146,814 CO September 01, 2026
25% $123,967 10% $117,547 90% $146,814 75% $139,286 $131,018 50%(Median) Didn’t find job title? Click
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Advanced Orthopedic Nurse Practitioner

MLee Healthcare Staffing and Recruiting, Inc - Denver, CO

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What is An Orthopedic Surgery Nurse Practitioner ?

An Orthopedic Surgery Nurse Practitioner (NP) specializes in providing comprehensive care to patients with musculoskeletal conditions. Responsibilities include conducting patient assessments, diagnosing orthopedic issues, developing treatment plans, and assisting in surgical procedures. NPs also educate patients on post-operative care and rehabilitation, ensuring optimal recovery. The salary for an Orthopedic Surgery Nurse Practitioner varies based on factors such as geographic location, years of experience, and the healthcare facility's size. On average, salaries range from $90,000 to $130,...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Jefferson, CO Avg. Salary $149,001 Date Updated September 01, 2026
Location Agate, CO Avg. Salary $145,930 Date Updated September 01, 2026
Location Aguilar, CO Avg. Salary $145,190 Date Updated September 01, 2026
Location Akron, CO Avg. Salary $145,706 Date Updated September 01, 2026
Location Alamosa, CO Avg. Salary $146,943 Date Updated September 01, 2026
Location Allenspark, CO Avg. Salary $152,266 Date Updated September 01, 2026
Location Alma, CO Avg. Salary $150,427 Date Updated September 01, 2026
Location Almont, CO Avg. Salary $151,254 Date Updated September 01, 2026
Location Amherst, CO Avg. Salary $145,239 Date Updated September 01, 2026
Location Anton, CO Avg. Salary $145,119 Date Updated September 01, 2026
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