As of January 01, 2026, the average annual salary for Orthopedic Surgery Nurse Practitioner in the US is $128,444, equivalent to $62 per hour, $2,470 weekly, or $10,704 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Orthopedic Surgery Nurse Practitioner in cities like Santa Clara, San Jose, and Fremont.

Annually Salaries for Orthopedic Surgery Nurse Practitioner in the US vary widely, spanning from $115,126 to $144,224. Most professionals fall between the 25th percentile ($121,473) and 75th percentile ($136,704), while top earners (90th percentile) make $144,224 per year. This $15,231 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, District of Columbia Orthopedic Surgery Nurse Practitioner often earn 10.7% above national averages due to demand from Fortune 47 companies and industry startups. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Orthopedic Surgery Nurse Practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Orthopedic Surgery Nurse Practitioner Salary $115,126 US January 01, 2026
25th Percentile Orthopedic Surgery Nurse Practitioner Salary $121,473 US January 01, 2026
50th Percentile Orthopedic Surgery Nurse Practitioner Salary $128,444 US January 01, 2026
75th Percentile Orthopedic Surgery Nurse Practitioner Salary $136,704 US January 01, 2026
90th Percentile Orthopedic Surgery Nurse Practitioner Salary $144,224 US January 01, 2026
25% $121,473 10% $115,126 90% $144,224 75% $136,704 $128,444 50%(Median) Didn’t find job title? Click
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What is An Orthopedic Surgery Nurse Practitioner ?

An Orthopedic Surgery Nurse Practitioner (NP) specializes in providing comprehensive care to patients with musculoskeletal conditions. Responsibilities include conducting patient assessments, diagnosing orthopedic issues, developing treatment plans, and assisting in surgical procedures. NPs also educate patients on post-operative care and rehabilitation, ensuring optimal recovery. The salary for an Orthopedic Surgery Nurse Practitioner varies based on factors such as geographic location, years of experience, and the healthcare facility's size. On average, salaries range from $90,000 to $130,...

Source: (as of 06/04/2025). Read more from

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Average Base Salary

Core compensation

 
 
 
121473
136704
128444

Average Total Cash Compensation

Includes base and annual incentives

 
 
 
131794
157625
144241
These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of Orthopedic Surgery Nurse Practitioner in the United States. The base salary for Orthopedic Surgery Nurse Practitioner ranges from $121,473 to $136,704 with the average base salary of $128,444. The total cash compensation, which includes base, and annual incentives, can vary anywhere from $131,794 to $157,625 with the average total cash compensation of $144,241.

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121473
136704

 

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