As of July 01, 2026, the average annual salary for Orthopedic Surgery Nurse Practitioner in the US is $128,420, equivalent to $62 per hour, $2,470 weekly, or $10,702 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Orthopedic Surgery Nurse Practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Orthopedic Surgery Nurse Practitioner in the US vary widely, spanning from $115,201 to $143,906. Most professionals fall between the 25th percentile ($121,500) and 75th percentile ($136,526), while top earners (90th percentile) make $143,906 per year. This $15,026 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, District of Columbia Orthopedic Surgery Nurse Practitioner often earn 10.7% above national averages due to demand from Fortune 47 companies and industry startups. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Orthopedic Surgery Nurse Practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Orthopedic Surgery Nurse Practitioner Salary $115,201 US July 01, 2026
25th Percentile Orthopedic Surgery Nurse Practitioner Salary $121,500 US July 01, 2026
50th Percentile Orthopedic Surgery Nurse Practitioner Salary $128,420 US July 01, 2026
75th Percentile Orthopedic Surgery Nurse Practitioner Salary $136,526 US July 01, 2026
90th Percentile Orthopedic Surgery Nurse Practitioner Salary $143,906 US July 01, 2026
25% $121,500 10% $115,201 90% $143,906 75% $136,526 $128,420 50%(Median) Didn’t find job title? Click
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What is An Orthopedic Surgery Nurse Practitioner ?

An Orthopedic Surgery Nurse Practitioner (NP) specializes in providing comprehensive care to patients with musculoskeletal conditions. Responsibilities include conducting patient assessments, diagnosing orthopedic issues, developing treatment plans, and assisting in surgical procedures. NPs also educate patients on post-operative care and rehabilitation, ensuring optimal recovery. The salary for an Orthopedic Surgery Nurse Practitioner varies based on factors such as geographic location, years of experience, and the healthcare facility's size. On average, salaries range from $90,000 to $130,...

Source: (as of 06/04/2025). Read more from

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Average Base Salary

Core compensation

 
 
 
121500
136526
128420

Average Total Cash Compensation

Includes base and annual incentives

 
 
 
135703
162126
148203
These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of Orthopedic Surgery Nurse Practitioner in the United States. The base salary for Orthopedic Surgery Nurse Practitioner ranges from $121,500 to $136,526 with the average base salary of $128,420. The total cash compensation, which includes base, and annual incentives, can vary anywhere from $135,703 to $162,126 with the average total cash compensation of $148,203.

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121500
136526

 

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