As of July 01, 2026, the average annual salary for Orthopedic Surgery Nurse Practitioner in North Carolina is $122,037, equivalent to $59 per hour, $2,347 weekly, or $10,170 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Orthopedic Surgery Nurse Practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for Orthopedic Surgery Nurse Practitioner in North Carolina vary widely, spanning from $109,475 to $136,754. Most professionals fall between the 25th percentile ($115,462) and 75th percentile ($129,741), while top earners (90th percentile) make $136,754 per year. This $14,279 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, North Carolina Orthopedic Surgery Nurse Practitioner often earn 5.0% lower than national averages due to demand from Fortune 47 companies. However, North Carolina currently ranks 36 nationwide for Orthopedic Surgery Nurse Practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
Orthopedic Surgery Nurse Practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Orthopedic Surgery Nurse Practitioner Salary $109,475 NC July 01, 2026
25th Percentile Orthopedic Surgery Nurse Practitioner Salary $115,462 NC July 01, 2026
50th Percentile Orthopedic Surgery Nurse Practitioner Salary $122,037 NC July 01, 2026
75th Percentile Orthopedic Surgery Nurse Practitioner Salary $129,741 NC July 01, 2026
90th Percentile Orthopedic Surgery Nurse Practitioner Salary $136,754 NC July 01, 2026
25% $115,462 10% $109,475 90% $136,754 75% $129,741 $122,037 50%(Median) Didn’t find job title? Click
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What is An Orthopedic Surgery Nurse Practitioner ?

An Orthopedic Surgery Nurse Practitioner (NP) specializes in providing comprehensive care to patients with musculoskeletal conditions. Responsibilities include conducting patient assessments, diagnosing orthopedic issues, developing treatment plans, and assisting in surgical procedures. NPs also educate patients on post-operative care and rehabilitation, ensuring optimal recovery. The salary for an Orthopedic Surgery Nurse Practitioner varies based on factors such as geographic location, years of experience, and the healthcare facility's size. On average, salaries range from $90,000 to $130,...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Aberdeen, NC Avg. Salary $133,815 Date Updated July 01, 2026
Location Advance, NC Avg. Salary $136,612 Date Updated July 01, 2026
Location Ahoskie, NC Avg. Salary $133,982 Date Updated July 01, 2026
Location Alamance, NC Avg. Salary $136,978 Date Updated July 01, 2026
Location Albemarle, NC Avg. Salary $136,726 Date Updated July 01, 2026
Location Albertson, NC Avg. Salary $132,983 Date Updated July 01, 2026
Location Alexander, NC Avg. Salary $135,759 Date Updated July 01, 2026
Location Alexis, NC Avg. Salary $141,040 Date Updated July 01, 2026
Location Alliance, NC Avg. Salary $132,589 Date Updated July 01, 2026
Location Almond, NC Avg. Salary $133,525 Date Updated July 01, 2026
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