As of September 01, 2026, the average annual salary for Orthopedic Surgery Nurse Practitioner in South Carolina is $120,321, equivalent to $58 per hour, $2,314 weekly, or $10,027 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Orthopedic Surgery Nurse Practitioner in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for Orthopedic Surgery Nurse Practitioner in South Carolina vary widely, spanning from $107,951 to $134,828. Most professionals fall between the 25th percentile ($113,846) and 75th percentile ($127,914), while top earners (90th percentile) make $134,828 per year. This $14,068 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, South Carolina Orthopedic Surgery Nurse Practitioner often earn 6.3% lower than national averages due to demand from Fortune 47 companies. However, South Carolina currently ranks 42 nationwide for Orthopedic Surgery Nurse Practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.
